GMP Operations Associate
Company
Vor Bio
Location
Cambridge
Type
Full Time
Job Description
We engineer stem cell transplants that shield healthy cells from targeted therapies
Targeted therapies work by attacking cells that express particular proteins on their surface. Unfortunately, both diseased and healthy cells often express the same proteins, resulting in collateral damage to healthy cells.
At Vor Bio, we engineer hematopoietic stem cells (HSCs) to lack a biologically redundant target protein, then transplant these cells into the patient.
These eHSCs give rise to generations of new healthy blood cells that are effectively shielded from targeted therapies so that only the remaining cancer cells are killed. We are also developing our own CAR-T cell therapy using T cells from the same healthy donor who could potentially provide HSCs for our shielded stem cell transplant and thereby, avoid issues of donor-mismatch. We believe our CAR-T cell therapy may enable more potent and durable responses post-transplant.
Vor Bio is aiming to cure blood cancers through our novel platform combining HSC biology, genome engineering, and targeted therapies to unlock treatment options previously unavailable to patients. Come be a part of a passionate team striving to collaboratively develop a groundbreaking approach to cancer treatment, one of medicine’s greatest challenges.
What we value in our fellow Voracians
Passion:Â Enthusiastically driving our science toward innovative medicines
Fellowship:Â Fostering genuine bonds of collaboration and mentorship
Humility: Acting selflessly by putting the collective mission first
Who we are looking for:
Vor Bio is seeking a GMP Operations Associate who is an enthusiastic and driven individual to support cGMP manufacturing for clinical phase cell therapy manufacturing facility. The candidate will be responsible for providing assistance in the support area for the manufacturing of Vor’s gene-edited cell therapies and maintaining compliance of cGMPs in manufacturing areas.Â
Key areas of responsibility:
- Support and perform cleanroom operations such as cleaning specialized equipment, restocking materials, sample transfer and document management
- Work with internal and external partners to track equipment preventative maintenance and calibration events and support equipment management in a computerized maintenance management system (CMMS)
- Coordinate with appropriate groups (Supply Chain, Safety, and Facilities) for material management, safety equipment checks and facility maintenance
- Responsible for material management in and out of the cleanrooms to support clinical production
- Responsible for waste management and working with internal partners for waste removal
- Strict adherence to current good manufacturing practices, standard operating procedures, and manufacturing documentation.
- Must be able to lift up to 50lbs.
Qualifications:
- HS diploma or BS in Biology or related field
- 1 - 3 years of hands-on experience with supporting manufacturing facility
- Cell therapy production support and aseptic manufacturing technique preferred
By becoming a team member here at Vor, you’ll have access to competitive health, dental, and vision coverage, as well as life insurance, and short term and long-term disability insurance. We value work life balance, you'll benefit from discretionary time off, parental leave, and an excellent 401(k) package. We also offer a generous transportation stipend to commute as you wish. We are conveniently located in Cambridge with easy access to public transportation and ample parking.
As an equal opportunity employer, we at Vor Bio know that diversity inspires innovation, inclusiveness, and creativity. We invite you to come as you are. All applicants will be considered for employment agnostic to race, age, color, religion, sex, sexual orientation, gender identity, national origin, veteran or disability status.
Please visit our website at https://www.vorbio.com/ for more information.
Date Posted
02/26/2024
Views
2
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