Postdoctoral Fellow- Immuno-Oncology

About City of Hope : City of Hope, an innovative biomedical research, treatment and educational institution with over 6000 employees, is dedicated to the prevention and cure of cancer and other life-threatening diseases and guided by a compassionate, patient-centered philosophy. Founded in 1913 and headquartered in Duarte, California, City of Hope is a remarkable non-profit institution, where compassion and advanced care go hand-in-hand with excellence in clinical and scientific research. City of Hope is a National Cancer Institute designated Comprehensive Cancer Center and a founding member of the National Comprehensive Cancer Network, an alliance of the nation's leading cancer centers that develops and institutes standards of care for cancer treatment.

Position Summary : Our group in the Department of Immuno-Oncology of the Beckman Research Institute at the City of Hope is interested in developing novel therapeutics for the treatment of difficult-to-treat malignancies occurring in the pancreas, lung and blood. We are currently exploring cancer vaccines to elicit immunity capable of eliminating cancers over-expressing tumor-specific antigens. The successful candidate will participate in laboratory research by performing bacterial, molecular, and mouse work to develop, characterize and evaluate efficacy of candidate agents.

Key Responsibilities include, but are not limited to :

• Recombinant bacterial maintenance
• Protein expression analysis
• Flow cytometric analysis
• Mouse handling (injections, collection of blood and tissues)
• Cell culture maintenance and assays involving mouse and human primary T cells (mouse splenocytes, mouse and human PBMCs)

Qualifications : Education, experience and skills required for consideration:

• Ph.D. in immunology, microbiology or related disciplines
• Meticulous record keeping, impeccable organization and proficiency with databases
• Exceptional organizational skills
• Excellent written and verbal communication
• Strong work ethic, highly motivated, and work well independently and in a team
• Hands-on experience in various dosing routes to mice and collecting blood and tissues, as well as processing samples for ex vivo analysis
• Extensive hands-on experience in primary T-cell culture and assays (mouse and human)
• Experience in imaging, flow cytometry and translational science

Background in cancer models and therapeutics is a plus.

Additional Information:

• To protect the health of patients and staff and to comply with new State of California mandates, City of Hope staff are required to show proof of full vaccination by September 30, 2021. Compliance is a condition of employment.

City of Hope is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, or status as a qualified individual with disability.

• Posting Date: Sep 7, 2021
• Job Field: Research
• Employee Status: Regular
• Shift: Day Job