Senior Research Associate/Scientist/Scientist

Kura Oncology, Inc. • San Diego, CA

Company

Kura Oncology, Inc.

Location

San Diego, CA

Type

Full Time

Job Description

Are you ready to join a team committed to making a meaningful impact on cancer treatment through the discovery and development of precision medicines? At Kura Oncology, you have an opportunity to be a part of something bigger, with a lasting impact that you can be proud of.

At Kura Oncology, we are working to change the paradigm and improve the science of cancer treatment. As an organization, we strive to cultivate a diverse and talented professional culture driven to develop precision medicine therapeutics.

As we continue to build a leading biotech organization with a strong culture, a patient-focused mindset and a team focused on relentless execution, we are looking for innovative, passionate professionals to join us and make our vision a reality.

To succeed at Kura, you will need to have a demonstrated ability for excellence in drug discovery and development and a roll-up your sleeves attitude. The ideal candidate will possess a values-driven work style where integrity and grit drive all behaviors, decisions, and actions.

ESSENTIAL JOB FUNCTIONS:

Kura Oncology’s lab in San Diego is looking for a bench scientist who is motivated, multiskilled and eager to learn with experience in molecular biology, cellular or biochemical techniques to support several translational research programs. The successful candidate will design, execute and troubleshoot biological assays and advanced cell cultures. The successful candidate will have deep experience in advanced molecular biology, mammalian cell culture techniques, and cellular and biochemical assay development. He/she will support the validation of multiple mechanisms of actions of our drug combinations, including testing the effects of compounds in cellular and biochemical settings. He/she will utilize or develop new technology to support all lab studies.

Scientific Responsibilities include:

  • Development of cellular and biochemical assays as required for various research projects ongoing in the lab.
  • Data analysis and presentation in internal meetings.
  • Support lab operations and lab maintenance
  • Successfully perform bench experiments independently or with limited input from a supervisor.

JOB SPECIFICATIONS:

  • M.S. in Molecular Biology/Cellular biology/Biochemistry or related discipline with 3-4+ years of experience, or Ph.D. in Molecular Biology/Cellular biology/Biochemistry or related discipline with 0-1 year experience in academia or industry. B.S with 5+ years in industry experience.
  • Extensive experience in basic molecular biology/biochemistry techniques such as western blot, qPCR and other molecular biology/biochemistry techniques
  • Extensive experience in basic cell culture experience. Experience in primary cell culture is preferred.
  • Proficient in tissue handling techniques such as protein extraction and RNA extraction.
  • Proficient in immunofluorescence including imaging processes using confocal microscope or equivalent.
  • Proficient in gene expression tools and techniques, including knockdown, overexpression, lenti-viral transduction…etc.
  • Experience in ChIP/ChIP-seq, RNA-seq or ATAC-seq is desirable.
  • Ability to conduct quantification analyses using designated software or applying statistical/mathematical methods, and ability to perform various analyses using software such as GraphPad or ImageJ.
  • Ability to conduct and troubleshoot experiments with minimum supervision.
  • Highly motivated, innovative, and strong team player. Excellent time management and organizational skills.Able to adapt quickly to changing needs of the company and work collaboratively.
  • Deliver results under tight deadlines.

The base range for this a Senior Research Associate is $58,000 - $72,000 per year, a Scientist would be $102,000 - $129,000. Individual pay may vary based on additional factors, including, and without limitation, job-related skills, experience, work location, and relevant education or training. Kura's compensation package also includes generous benefits, equity, and participation in an annual target bonus.

Kura’s Values that are used for candidate selection and performance assessments:

  • We work as one for patients
  • We are goal-focused and deliver with excellence
  • We are science-driven courageous innovators
  • We strive to bring out the best in each other and ourselves

The Kura Package

  • Career advancement/ development opportunities
  • Competitive comp package
  • Bonus
  • 401K + Employer contributions
  • Generous stock options
  • ESPP Plan
  • 20 days of PTO to start
  • 18 Holidays  (Including Summer & Winter Break)
  • Generous Benefits Package with a variety of plans available with a substantial employer match
  • Paid Paternity/Maternity Leave
  • In-Office Catered lunches
  • Home Office Setup
  • Lifestyle Spending Stipend
  • Commuter Stipend (Boston Office)
  • Regular employee social activities, including happy hours, monthly birthday celebrations, Kura Koffee Talks, and much more!

Kura Oncology is a clinical-stage biopharmaceutical company discovering and developing personalized therapeutics for the treatment of solid tumors and blood cancers. The company’s diverse pipeline consists of small molecules that target cancer signaling pathways where there is a strong scientific and clinical rationale to improve outcomes by identifying those patients most likely to benefit from treatment. Kura Oncology’s approach to drug development is focused on rapidly translating novel science into life-saving medicines. Our goal is to help patients with cancer lead better, longer lives. Kura Oncology has offices in San Diego, California, and Boston, Massachusetts.

Kura’s pipeline consists of three investigational drug candidates: ziftomenib, tipifarnib and KO-2806. Ziftomenib is a once-daily, oral drug candidate targeting the menin-KMT2A protein-protein interaction for the treatment of genetically defined AML patients with high unmet need. Ziftomenib is currently enrolling patients in a Phase 2 registration-directed trial (KOMET-001) in NPM1-mutant relapsed or refractory AML. Kura is preparing to initiate multiple Phase 1 trials to evaluate ziftomenib in combination with current standards of care in earlier lines of therapy and across multiple patient populations, including NPM1-mutant and KMT2A-rearranged AML. Tipifarnib, a potent and selective FTI, is currently in a Phase 1/2 trial (KURRENT-HN) in combination with alpelisib for patients with PIK3CA-dependent HNSCC. Kura intends to evaluate KO-2806, a next-generation FTI, in a Phase 1 dose-escalation trial (FIT-001) as a monotherapy and in combination with other targeted therapies in adult patients with advanced solid tumors. For additional information, please visit Kura’s website at www.kuraoncology.com. 

Kura Oncology is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, disability, age, or veteran status. 

Apply Now

Date Posted

02/29/2024

Views

2

Back to Job Listings ❤️Add To Job List Company Info View Company Reviews
Positive
Subjectivity Score: 0.8

Similar Jobs

Store Associate - CVS Health

Views in the last 30 days - 0

View Details

Store Associate - CVS Health

Views in the last 30 days - 0

View Details

Store Associate - CVS Health

Views in the last 30 days - 0

View Details

CYP Child and Youth Program Assistant - Multi-Level - Department of the Navy - Commander, Navy Installations

Views in the last 30 days - 0

View Details

Software Developer in Test, Apple Pay - Apple

Views in the last 30 days - 0

View Details

Software Engineer - Data - Apple

Views in the last 30 days - 0

View Details