Senior Scientist, Bioconjugates

Janssen Research & Development, LLC, a member of Johnson & Johnson's Family of Companies, is recruiting for a Senior Scientist, Bioconjugates located in Spring House, PA.

At the Janssen Pharmaceutical Companies of Johnson & Johnson, what matters most is helping people live full and healthy lives. We focus on treating, curing and preventing some of the most devastating and complex diseases of our time. And we pursue the most promising science, wherever it might be found.

Janssen Research & Development, LLC discovers and develops innovative medical solutions to address important unmet medical needs in oncology, immunology, neuroscience, infectious diseases and vaccines, cardiovascular and metabolism, and pulmonary hypertension. Please visit http://www.janssenrnd.com for more information.

The Bioconjugates group within Global Discovery Chemistry is a part of Therapeutics Discovery and is engaged in developing novel therapeutics across bioconjugate modalities including Antibody-drug Conjugates (ADCs), Radioligand Therapies (RLTs), and siRNA conjugates.

We are looking for a talented, highly motivated, and technically proficient Senior Scientist, Bioconjugates to become part of our team. This individual will have a background in protein/peptide chemistry, bioconjugate chemistry, antibody discovery, or a related field with a record of developing new technologies and achieving research goals on aggressive timelines through effective cross-functional collaboration. Utilize experience in discovery or development of targeted therapeutics such as ADCs, peptide/small molecule conjugates, or nucleic acid conjugates (siRNA, antisense, etc.) as well as analytical characterization of these products.

Principal Responsibilities:

• Design and execute new project ideas (design and execution of studies, analysis of data, presentation of results) to support multiple research programs and provide critical data to inform decisions in a cross-functional team.
• Lead teams to accomplish tasks and achieve project objectives.
• Collaborate with the therapeutic areas and other groups to define strategies and deliver stage-appropriate molecules for preclinical studies.
• Keep abreast of new technologies/capabilities relevant to this role and strive to implement them to advance research projects.
• Author data summaries, technical reports, standard operating procedures, publications, and presentations.

Qualifications

• A minimum of a Bachelor's degree in Chemistry, Biochemistry, Chemical/Biomedical Engineering, or other related scientific discipline is required. Advanced degree (Master's, Ph.D.) degree in Chemistry, Biochemistry, Chemical/Biomedical Engineering, or other related scientific discipline is preferred.
• A minimum of 8 years of relevant research experience with a Bachelor's degree; a minimum of 6 years of relevant research experience with a Master's degree; or a minimum of 2 years of relevant research; or post-doc experience with a PhD degree is required.
• Experience with bioconjugation methods, protein biochemistry, and/or peptide chemistry is required.
• Experience with biomolecule purification using automated chromatography systems is required.
• Experience with Liquid Chromatography/Mass Spectrometry (LC/MS) characterization of large molecules is preferred.
• A solid research record demonstrated by patents, publications, or presentations in the area of targeted drug delivery or bioconjugates is preferred.
• Must have excellent oral and written communication and presentation skills.
• Must be organized, self-motivated and capable of working independently and in a collaborative multi-disciplinary environment.
• Must be flexible to adjust priorities over time to meet organizational and scientific goals.
• The ability to work in fast-paced environment and handle multiple tasks while meeting timelines is required.
• The ability to lead projects and work productively in an interdisciplinary team environment is required.

Johnson & Johnson is an Affirmative Action and Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, or protected veteran status and will not be discriminated against on the basis of disability.