Senior Scientist, In Vitro Toxicology

Job Description

Scientists in the In Vitro Toxicology group within the Investigative Toxicology function of Nonclinical Drug Safety (NDS) contribute to the advancement of our company's discovery pipeline through the development and application of novel in vitro models/assays to support nonclinical safety testing and derisking effort. This specific position is expected to contribute to strategy and execution of various in vitro toxicology projects, provide scientific leadership, and drive innovation and new capability development. The successful candidate should have in depth knowledge and experience of in vitro model/assay development and application pertaining to nonclinical drug safety testing, demonstrated ability of delivering results, problem solving, and collaboration across disciplines.

Qualifications

Education requirement:

• Doctoral degree in Toxicology, Pharmacology, Bioengineering or a closely related discipline

Key responsibilities include:

• Lead various in vitro toxicology projects, contribute to both strategy and execution, to support nonclinical risk assessment and investigative problem-solving.
• Ensure robust delivery of study results, including accurate recording of experimental data in electronic laboratory notebooks and generation of study reports.
• Provide scientific leadership to junior scientists and technical staff, assist with troubleshooting.
• Collaborate effectively with internal and external partners to drive innovative solutions to nonclinical safety problems and develop new capabilities for investigative toxicology and other nonclinical safety needs.

Required Experience and Skills:

• Minimal 3 years working experience in nonclinical drug safety testing, preferably in an industry setting
• Knowledge and hands-on experience in the development and application of complex in vitro models and novel in vitro assays for nonclinical safety testing
• Strong communication skills, with the ability to interact effectively with colleagues across various functional teams

Preferred Experience and Skills:

• Knowledge and experience of drug discovery and development process, and the use of complex in vitro models in nonclinical safety testing
• Expertise and experience in designing, developing, implementing and troubleshooting lab automation, high throughput in vitro assays, and high content imaging-based endpoints
• Expertise and experience in applying PKPB modeling to complex in vitro models to enable IVIVC

Current Employees apply HERE

Current Contingent Workers apply HERE

US and Puerto Rico Residents Only:

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We are an Equal Opportunity Employer, committed to fostering an inclusive and diverse workplace. All qualified applicants will receive consideration for employment without regard to race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status, or other applicable legally protected characteristics. For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit:

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We are proud to be a company that embraces the value of bringing diverse, talented, and committed people together. The fastest way to breakthrough innovation is when diverse ideas come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another's thinking and approach problems collectively.

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U.S. Hybrid Work Model

Effective September 5, 2023, employees in office-based positions in the U.S. will be working a Hybrid work consisting of three total days on-site per week, Monday - Thursday, although the specific days may vary by site or organization, with Friday designated as a remote-working day, unless business critical tasks require an on-site presence.This Hybrid work model does not apply to, and daily in-person attendance is required for, field-based positions; facility-based, manufacturing-based, or research-based positions where the work to be performed is located at a Company site; positions covered by a collective-bargaining agreement (unless the agreement provides for hybrid work); or any other position for which the Company has determined the job requirements cannot be reasonably met working remotely. Please note, this Hybrid work model guidance also does not apply to roles that have been designated as "remote".

San Francisco Residents Only: We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance

Los Angeles Residents Only: We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles' Fair Chance Initiative for Hiring Ordinance

Search Firm Representatives Please Read Carefully
Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.

Employee Status:
Regular

Relocation:
Domestic/International

VISA Sponsorship:
Yes

Travel Requirements:
10%

Flexible Work Arrangements:
Not Applicable

Shift:
Not Indicated

Valid Driving License:
No

Hazardous Material(s):
N/A

Job Posting End Date:
01/17/2025
*A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.

Requisition ID:R328094