Sr Assoc. Scientist/Assoc. Scientist, Flow Cytometry(Contractor)

About Allogene Therapeutics, Inc:

Allogene Therapeutics is a clinical-stage biotechnology company with a single-minded focus on pioneering the development of investigational allogeneic chimeric antigen receptor T cell (AlloCAR T™) products for cancer. Led by world-class management with significant experience in cell therapy, our fully integrated, in-house team of researchers is dedicated to discovery and translational research, development, and cell manufacturing.

At Allogene, we are developing a pipeline of off-the-shelf CAR T cell candidates, with the goal of delivering readily available cell therapy faster, more reliably, and at greater scale to more patients. For more information, please visit www.allogene.com, and follow @AllogeneTx on Twitter and LinkedIn.

About the role:

Allogene is seeking a highly determined, results-oriented, self-starter who demonstrates personal accountability for outcomes and is motivated by increasing levels of responsibility, to join a dynamic team responsible for successful development and characterization of clinical-scale manufacturing of Allogeneic Chimeric Antigen Receptor T-cell therapies (Allo CAR T™). The successful candidate will help to support appropriate flow cytometry-based analytical methods for the characterization, release and stability testing of CAR T products. This position will also contribute to the development of novel technologies and approaches to meet future CAR T analytical needs and work in close collaboration with key stakeholders, including the CAR T Research and Process Development groups.

Responsibilities include, but are not limited to:

• Actively contribute to successful and efficient execution of robust, state-of-the-art multicolor flow cytometry methods for the characterization of CAR T manufacturing processes and products
• Provide analytical support for clinical-scale non-GMP IND-enabling manufacturing operations, including qualification of in-process and release methods and tech transfer internally and externally in support of GMP manufacturing and release of clinical material.
• Contribute to project technical teams to ensure effective communication at all levels. Collaborate effectively to ensure productive interactions with all stakeholder groups.
• Demonstrate strong accountability, organizational and interpersonal skills, and apply sound scientific and technical experience.
• Ensure high-quality, timely documentation in electronic laboratory notebooks and technical reports which support regulatory filings.
• Present data/ strategy to scientists and management in internally.

Position Requirements & Experience:

• Bachelor’s degree or master’s degree in immunology, cell biology or related field is required (or relevant experience).
• Associate Scientist requires BS with 1-5 years of experience in similar role in biotechnology industry is preferred
• Senior Associate Scientist requires BS 5-8, MS 2-5 years of experience in similar role in biotechnology industry is preferred
• Laboratory experience in a variety of analytical methods for the characterization and release of cell-based therapies, especially multi-parametric flow cytometry-based assays for characterization/ release/ stability testing.
• Hands-on expertise in handling and processing of primary peripheral blood mononuclear cells or cell culture (required) and analysis of T cell subsets and subpopulations (desired).
• Proficiency in data analysis and interpretation using FlowJo would be advantageous.
• Familiarity with cGMPs and relevant Regulatory Guidance documents.
• Excellent organizational skills and an ability to prioritize effectively to deliver results within reasonably established timelines.
• Ability to work independently and as part of a team.
• Strong interpersonal skills including verbal and written communication are essential in this collaborative work environment.
• Candidates must be authorized to work in the U.S.

As an equal opportunity employer, Allogene is committed to a diverse workforce. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, gender, age, sexual orientation, physical or mental disability, genetic information or characteristic, gender identity and expression, veteran status, or other non-job related characteristics or other prohibited grounds specified in applicable federal, state and local laws. We also embrace differences in experience and background, and welcome diversity of opinions and thought with active recruitment and internships designed to create a stronger and better Allogene that is focused on developing life-changing products for patients.

Please be aware that the FBI recently issued a warning about an increased number of fake job postings for remote work employment that target applicants' personally identifiable information. All approved Allogene Therapeutics positions are accessible via the Allogene Careers page at www.allogene.com/careers.