Jobs at Click Therapeutics
249,921 open positions
Executive Director, DMPK
Company: Nimbus Therapeutics
Location: Boston, MA
Posted Apr 03, 2024
<p><strong>Nimbus has an outstanding opportunity for an exceptional Executive Director DMPK to join our team This role will serve as the function head applying subject matter expertise in absorption distribution metabolism and excretion ADME pharmacokinetics and pharmacodynamics along with effective team management skills to drive the strategy and execution of our clinical development and preclinical programs You will report to our Senior Vice President of Nonclinical Sciences<strong><p> <p><strong>In this role you will<strong><p> <ul><li>Design and execute preclinical studies to understand the pharmacokinetics PK and absorption metabolism distribution and excretion ADME of drug candidates that support drug discovery preclinical and clinical development<li> <li>Responsible for the analysis interpretation integration and reporting of preclinical DMPK data generated both internally and with external collaborators<li> <li>Represent DMPK as the subject matter expert to project teams<li> <li>Provide leadership and management support for nonclinical DMPK that can build and inspire our teams and drive collaboration and innovation<li> <li>Establish effective relationships with CROs consultants and internal team members to develop and qualify various analytical and bioanalytical methods<li> <li>Design contract and manage CRO in the conduct of in vitro in vivo ADME studies Review study protocols and reports interpret and communicate results<li> <li>Prepare strategic and scientifically sophisticated ADME strategies that meet regulatory requirements and program goals<li> <li>Author review and approve scientific reports that support regulatory documents including INDs CTAs and NDA filings<li> <li>Partner with and support Toxicology Research Clinical Regulatory Project Management and other departments<li> <li>Provide leadership and management support for nonclinical DMPK that can build and inspire our teams and drive collaboration and innovation<li> <ul><p><strong>These Qualifications Will Help This Role Be Successful<strong><p> <ul><li>PhD in Pharmacokinetics Pharmacology Pharmaceutical Science or other relevant field with 15+ years of experience in the biopharmaceutical industry<li> <li>Strong knowledge of smallmolecule drug metabolism ADME concepts pharmacokinetics pharmacodynamic and bioanalytical principles<li> <li>Track record of success with clinical development phases<li> <li>Ability and Interest in leading dynamic multidisciplined project teams<li> <li>Prior experience with regulatory submission eg IND NDA andor BLA preferred<li> <li>Working knowledge in various modeling techniques and programing preferred<li> <li>Excellent verbal and written communication and organizational skills required with experience working on cross functional teams<li> <li>Ability to navigate problemsolve execute and lead in a dynamic fastpaced and evolving environment<li> <ul><div> <p><strong><span datacontrast=none>A Snapshot of Nimbus<span><strong><span dataccpprops=> <span><p> <p><em><span datacontrast=none>Our <span><em><em><span datacontrast=none>S<span><em><em><span datacontrast=none>cience <span><em><span dataccpprops=> <span><p> <p><span datacontrast=none>At Nimbus we design breakthrough medicines Utilizing our powerful structurebased drug discovery engine we create potent and selective small molecule compounds targeting proteins that are known to be fundamental drivers of pathology in highly prevalent human diseases and which have proven difficult for other drug makers to tackle With a decadeplus track record of success <span><span datacontrast=none>weve<span><span datacontrast=none> built a worldclass team in both computationally driven drug discovery and early clinical development while continuing to move the needle for patients <span><span dataccpprops=> <span><p> <p><em><span datacontrast=none>Our <span><em><em><span datacontrast=none>C<span><em><em><span datacontrast=none>ulture<span><em><span dataccpprops=> <span><p> <p><span datacontrast=none>Nimbus <span><span datacontrast=none>is a<span><span datacontrast=none> closeknit <span><span datacontrast=none>company<span><span datacontrast=none> our employees are <span><span datacontrast=none>Nimbi if you are curious<span><span datacontrast=none> that <span><span datacontrast=none>values a fastpaced entrepreneurial<span><span datacontrast=none> intellectual<span><span datacontrast=none>stimulating<span><span datacontrast=none> and collaborative <span><span datacontrast=none>environment <span><span datacontrast=none>We live by o<span><span datacontrast=none>ur Core Values Integrity a Passion for Excellence Teamwork and Authentic Communication<span><span datacontrast=none> <span><span datacontrast=none>and strive to build a community where we bring out the best in each other<span><span datacontrast=none> professionally and personally <span><span dataccpprops=> <span><p> <p><em><span datacontrast=none>Our Company<span><em><span dataccpprops=> <span><p> <p><span datacontrast=none>Founded in 2009 <span><span datacontrast=none>Nimbus is a private<span><span datacontrast=none> growing<span><span datacontrast=none> biotechnology company headquartered in Boston <span><span datacontrast=none>Massachusetts<span><span datacontrast=none> <span><span datacontrast=none>Learn more about us by going to <span><span datacontrast=none>wwwnimbustxcom<span><span dataccpprops=> <span><p> <p><strong><span datacontrast=none>Join Nimbus We are making a difference and you can too<span><strong><span dataccpprops=> <span><p> <p><em>At Nimbus we believe our diversity of backgrounds and experiences strengthens our community and our ability to design breakthrough medicines We prioritize creating an inclusive welcoming culture that promotes our core values and encourages every Nimbi to bring their whole selves to their work Nimbus is proud to be an equal opportunity employer We value and celebrate all our employees and recognize that our diversity and inclusion are keys to our success Nimbus is committed to providing equal opportunity for all employees and applicants without regard to race color gender gender identity sexual orientation age religion national or ethnic origin disability protected veteran status or any other basis protected by applicable law Nimbus does not accept unsolicited resumes from any source other than directly from candidates<em><p> <p><span dataccpprops=> <span><p> <div>
Sr. Research Associate I, Genomics and Next Generation Sequencing
Company: Scribe Therapeutics
Location: East Bay
Posted Apr 03, 2024
Scribe Therapeutics, a molecular engineering company founded by CRISPR inventors, is seeking a Senior Research Associate to join their Technology Platform Team. The candidate should have a strong background in molecular biology, NGS, and synthetic biology. Key responsibilities include generating high throughput sequencing data sets, designing and executing studies, collaborating with team members, and contributing to novel assay development. The role offers opportunities for professional growth and publishing impactful work. Required skills include a degree in a related field, 5+ years of experience in NGS assay development, proficiency in molecular genetics techniques, and familiarity with sequencing platforms. Preferred skills include industry experience, familiarity with long-read sequencing, and experience with CRISPR-Cas gene editing systems.
Head of Biochemistry and Biophysics
Company: MOMA Therapeutics
Location: Cambridge
Posted Apr 03, 2024
MOMA Therapeutics is seeking an experienced Head of Biochemistry and Biophysics. The successful candidate will lead a team, contribute to drug discovery programs, and play a key role in new target identification and platform development. The role requires a PhD in biochemistry or related field, at least 10 years of experience in biopharmaceutical research, and demonstrated experience in all stages of small molecule drug discovery, particularly in oncology. The individual should possess strong leadership skills, cross-functional team collaboration experience, and complex problem-solving abilities.
Director, CMC Analytical
Company: Maze Therapeutics
Location: Peninsula
Posted Apr 03, 2024
Maze Therapeutics is seeking a Director of CMC Analytical to join their Technical Operations leadership team. The role involves developing and executing analytical strategies for early-phase small molecule programs, leading method development and validation, setting product specifications, and overseeing QC testing at CMOs. The Director will report to the VP of Technical Operations and collaborate closely with the CMC team. Key responsibilities include creating a forward-thinking analytical development strategy, designing phase-appropriate specifications, overseeing analytical activities at third-party labs, reviewing CMO documents, managing internal method development and stability studies, collaborating with QA, contributing to regulatory filings, and demonstrating leadership competencies such as effective communication, teamwork, execution, and development of others.
Procurement Specialist
Company: Fate Therapeutics Inc
Location: San Diego, CA
Posted Apr 03, 2024
Fate Therapeutics is hiring for a Procurement position in San Diego, CA. The role involves managing Procure-to-Pay processes, engaging with cross-functional teams, and ensuring materials meet manufacturing and development timelines. The ideal candidate should have a Bachelor's degree, relevant experience in sourcing or procurement, and knowledge of cell therapy manufacturing regulations. The position offers a competitive salary range of $73,000 - $83,000 and a comprehensive benefits package.
TMF (Trial Master File) Specialist
Company: Apogee Therapeutics
Location: Remote
Posted Apr 02, 2024
Apogee Therapeutics, a Nasdaq-listed biotech company founded in 2022, is seeking a Trial Master File Specialist. The role involves managing TMF files, ensuring adherence to ICH-GCP guidelines, and working with CROs. The ideal candidate should have a science/healthcare degree, 5+ years of clinical operations and TMF experience, proficiency in MS Office Suite, and understanding of the clinical trial lifecycle. The company offers a competitive salary, flexible PTO, and commitment to professional growth.
Senior System Administrator
Company: Strand Therapeutics
Location: Boston, MA
Posted Apr 03, 2024
Strand Therapeutics, an early-stage biotech company in Boston, is seeking a Senior System Administrator. The role involves supporting IT initiatives, troubleshooting hardware problems, installing applications, educating users on security, analyzing system logs, performing backups, and collaborating with the founding team. The ideal candidate should have a degree in IT or related field, 5+ years of systems administration experience, and experience with Microsoft cloud platforms. Strand offers a dynamic work environment, competitive benefits, and opportunities for professional growth.
Director/Associate Director CMC Program Leadership
Company: MOMA Therapeutics
Location: Cambridge
Posted Apr 03, 2024
MOMA Therapeutics is seeking an experienced Associate Director/Director of CMC Project Leadership to lead small molecule CMC teams through preclinical development, IND filings, and clinical development. The role involves establishing CMC program strategy, overseeing external manufacturing activities, and representing the CMC function at the program level. The ideal candidate has at least 7 years of experience in small molecule CMC, experience with CDMOs, and a track record of authoring regulatory filings. MOMA Therapeutics is an equal opportunity employer.
Scientist II, High Throughput Screening- CNS
Company: Scribe Therapeutics
Location: East Bay
Posted Apr 03, 2024
Scribe Therapeutics, a molecular engineering company founded by CRISPR inventors, seeks a passionate and motivated Scientist for their high-throughput gRNA screening team. The ideal candidate will have a PhD in Bioengineering, Genomics, Molecular Biology, or equivalent, and at least 2 years of experience in developing and executing high-throughput assays in mammalian cells. They should be proficient in programming (Python or R), bioinformatics, and have strong communication skills. The role offers opportunities for professional growth, leadership, and publishing impactful work. The company is committed to diversity and offers a competitive salary range of $120,000-150,000 per year.
Assoc. Director/Director, Procurement
Company: Scribe Therapeutics
Location: East Bay
Posted Apr 03, 2024
Scribe Therapeutics, a molecular engineering company specializing in CRISPR-based genetic medicine, is seeking an Associate Director or Director of Procurement. The role involves managing order management, developing strategic supplier relationships, negotiating contracts, collaborating with various teams, driving process improvements, and leading procurement trainings. The ideal candidate should have a degree in a related field, at least 10 years of experience in supply chain or procurement management in the pharma or biotech industry, and expertise in vendor management, contract reviews, and purchase negotiations. The company offers a competitive salary, intellectually stimulating environment, and comprehensive benefits.
Search Engine Optimization Manager
Company: Click Here Digital
Location: Baton Rouge, LA
Posted Apr 03, 2024
The SEO Manager will lead a team of 20-30 professionals, managing SEO strategies, client deliverables, and team growth. They will collaborate with C-Suite, craft partner marketing strategies, and provide expert guidance on SEO best practices. The role requires a deep technical understanding of SEO, strong communication skills, and proficiency in various SEO tools. Preferred qualifications include experience in automotive, legal, or medical verticals and the ability to handle multiple clients.
Genesis Therapeutics - ML Research Engineer – New Grad
Company: Genesis Therapeutics
Location: Burlingame, CASan Diego, CA
Posted Apr 02, 2024
Genesis Therapeutics is seeking an ML Research Engineer for a new graduate position in Burlingame, CA or San Diego, CA. The job posting was made on April 02.