Advisor - TS/MS

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We're looking for people who are determined to make life better for people around the world.

Responsibilities:

TSMS Advisors at Lilly are responsible for:

• Ensuring reliability of our manufacturing systems
• Searching for and implementing continuous improvements
• Driving technical projects
• Maintaining our processes in a state of compliance with US and global regulations
• Designing and developing drug processes and delivery systems

The position is an Advisor position in the Technical Services/Manufacturing Science (TS/MS) organization. The position will be made available beginning March of 2024 and will provide technical and scientific support within a dynamic manufacturing environment for development of commercial processes (synthesis and purification) for biomolecules including proteins, peptides, and oligonucleotides. The successful candidate will be responsible for designing and executing experiments to advance process knowledge, process optimization and production technical transfer, as needed. Specifically experiments and expertise are desired in peptide and protein crystallization as well as crystallization scale up experience.

Scientists actively contribute to the TS/MS organization, and have extensive opportunities for involvement in cross-functional teams. This position allows for development of a comprehensive understanding of the pharmaceutical industry, Good Manufacturing Practices (GMP), regulatory requirements, and the essential role scientists play in making medicine and creating real-world solutions.

Key Objectives/Deliverables:

• Understanding the scientific principles required for manufacturing intermediates and drug substances, including the interaction of chemistry and equipment.
• Understand the chemistry and stability of biomolecules.
• Develop appropriate laboratory-scale models for key process steps in synthesis and/or purification of biomolecules, focused on crystallization.
• Design, conduct, and analyze statistically-designed experiments to deepen process understanding and optimize processing conditions.
• Understand scale-up requirements and, as needed, partner with the pilot plant to conduct appropriate scale-up work.
• Provide technical support for process development areas if needed.
• Strong technical writing and documentation of all work in an appropriate manner.
• Mentor lab associates to enhance their technical capabilities.
• Participate in technology transfer as needed.
• Ability to work well independently and collaboratively.

Basic Requirements:

• Enrolled in a Ph.D. program in scientific disciplines of Biochemistry, Biology, Molecular Biology, Microbiology, Pharmacology, Chemistry or related fields with completion of degree by August 2023.
• Demonstrated experience and proficiency in the areas of protein, oligonucleotide, and peptide chemistry and/or purification.
• Requires a record of publication in peer reviewed journals and presentations / posters at scientific conferences.

Eli Lilly and Company, Lilly USA, LLC and our wholly owned subsidiaries (collectively "Lilly") are committed to help individuals with disabilities to participate in the workforce and ensure equal opportunity to compete for jobs. If you require an accommodation to submit a resume for positions at Lilly, please email Lilly Human Resources ( [email protected] ) for further assistance. Please note This email address is intended for use only to request an accommodation as part of the application process. Any other correspondence will not receive a response.

Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.

Our employee resource groups (ERGs) offer strong support networks for their members and help our company develop talented individuals for future leadership roles. Our current groups include: Africa, Middle East, Central Asia Network, African American Network, Chinese Culture Network, Early Career Professionals, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinos at Lilly, PRIDE (LGBTQ + Allies), Veterans Leadership Network, Women's Network, Working and Living with Disabilities. Learn more about all of our groups.

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