Associate Scientist (Contract)

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About Allogene Therapeutics, Inc:

Allogene Therapeutics, with headquarters in South San Francisco, is a clinical-stage biotechnology company pioneering the development of allogeneic chimeric antigen receptor T cell (AlloCAR T™) therapies for cancer. Led by a management team with significant experience in cell therapy, Allogene is developing a pipeline of “off-the-shelf” CAR T cell therapy candidates with the goal of delivering readily available cell therapy on-demand, more reliably, and at greater scale to more patients. For more information, please visit www.allogene.com, and follow @AllogeneTx on Twitter and LinkedIn.

Allogene is seeking a highly determined, results-oriented, self-starter who demonstrates personal accountability for outcomes and is motivated by increasing levels of responsibility, to join a dynamic team responsible for successful development and characterization of clinical-scale manufacturing of Allogeneic Chimeric Antigen Receptor T-cell therapies (Allo CAR T™). The successful candidate will help to support appropriate flow cytometry-based analytical methods for the characterization, release and stability testing of CAR T products. This position will also contribute to the development of novel technologies and approaches to meet future CAR T analytical needs and work in close collaboration with key stakeholders, including the CAR T Research and Process Development groups. This is a 1-year contract position in South San Francisco, CA.

Responsibilities include, but are not limited to:

• Actively contribute to successful and efficient execution of robust, state-of-the-art multicolor flow cytometry methods for the characterization of CAR T manufacturing processes and products.
• Provide analytical support for clinical-scale non-GMP IND-enabling manufacturing operations, including qualification of in-process and release methods and tech transfer internally and externally in support of GMP manufacturing and release of clinical material.
• Contribute to the biological interrogation of CAR T products.
• Contribute to project technical teams to ensure effective communication at all levels. Collaborate effectively to ensure productive interactions with all stakeholder groups.
• Demonstrate strong accountability, organizational and interpersonal skills, and apply sound scientific and technical experience.
• Ensure high-quality, timely documentation in electronic laboratory notebooks and technical reports which support regulatory filings.
• Present data/ strategy to scientists and management internally.

Position Requirements & Experience:

• BSc or Msc degree with a minimum of 1+ year of biotech industry experience in immunology, cell biology, or related field.
• Laboratory experience in a variety of analytical methods for the characterization/release/stability testing of cell-based therapies, especially multi-parametric flow cytometry-based assays.
• Hands-on expertise in handling primary peripheral blood mononuclear cells and immune cell isolation.
• Experience with cell culture, cell-based assays, and analysis of T cell subsets is highly desired.
• Proficiency in data analysis, including high-parameter analyses and interpretation using FlowJo or other flow cytometry analysis platforms is highly desired.
• Proficiency in R or other programming language would be advantageous.
• Excellent organizational skills and an ability to prioritize effectively to deliver results within reasonably established timelines.
• Ability to work both independently and as part of a team.
• Strong interpersonal skills including verbal and written communication are essential in this collaborative work environment.
• Candidates must be authorized to work in the U.S.

As an equal opportunity employer, Allogene Inc. is committed to a diverse workforce. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, gender, age, sexual orientation, physical or mental disability, genetic information or characteristic, gender identity and expression, veteran status, or other non-job related characteristics or other prohibited grounds specified in applicable federal, state and local laws.

Please be aware that the FBI recently issued a warning about an increased number of fake job postings for remote work employment that target applicants' personally identifiable information. All approved Allogene Therapeutics positions are accessible via the Allogene Careers page at www.allogene.com/careers.

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