Associate Scientist II, Process Sciences Innovation

How you’ll make an impact:

As an Associate Scientist II reporting to a Scientist II, you will lead laboratory experiments involving primary human immune cell isolation (PBMCs and T-cells), genetic modification (viral transduction and/or electroporation), T-cell expansion, and cryopreservation.

About the team:

The Cellular Process Development department is all about developing and characterizing processes to manufacture high quality reprogrammed T cells for our patients. Whether it is a deep understanding of the science and the engineering behind our product, the design and control of consistent and robust manufacturing processes, or the smooth progression of our product from pre-clinical to commercial manufacturing, we are driven by our commitment to give time back to our patients. Come work with an incredibly talented group of employees, that loves rising to the challenge much as we do, defeating cancer!

How you’ll spend your time:

• Leading laboratory experiments involving primary human immune cell isolation (PBMCs and T-cells), genetic modification (viral transduction and/or electroporation), T-cell expansion, and cryopreservation.
• Driving the authoring, reviewing, and maintaining accurate and up to date records including experimental databases, production batch records, laboratory notebooks, quality facing reports, technology transfer documentation, and regulatory documentation.
• Helping to develop and mature our next generation platform manufacturing process through innovative tools and techniques.
• Working with senior members to accomplish staying current on literature, process conceptualization and experimental design.
• Successfully applying statistical and data visualization techniques to interpret and present experimental results, and using good technical communication skills to report and document scientific findings.
• Performing administrative duties including personnel and lab operations scheduling.

Who you are and what you’ve accomplished:

• Have BS, BSc or equivalent with 2+ years of relevant experience in a laboratory environment or an MS/MSc or equivalent with 1+ years of relevant experience in a laboratory environment preferably in the field of cell biology, immunology, gene therapy, pharmaceutical, biological sciences or related discipline.
• Are experienced in mammalian cell culture, preferably in T-flasks, static expansion bags, stirred tank reactors, and/or rocking bioreactor platforms, with a strong understanding of general laboratory techniques related to tissue culture and bioprocessing.
• Are familiar with statistical analysis, data visualization, and design of experiments (DoE); preferred experience in JMP and Prism software, Microsoft Office suite, sufficient to author, review, revise, and present scientific data and/or reports.
• Have excellent organizational, time management, and interpersonal skills, capable of multi-tasking and prioritization under shifting business needs and in highly matrixed teams.
• Are passionate about: Hands-on benchwork requiring a flexible schedule based on experimental work (some weekend work may be required depending on experiments occurring over >5 days).