Associate Scientist/Senior Research Associate, Downstream Development

ShapeTX® is pioneering the field of programmable RNA medicines to repair the genetic causes of diseases. By merging innovations in AI and RNA technology to generate and analyze hundreds of billions of therapeutic possibilities, ShapeTX is developing breakthroughs in RNA editing, next-generation AAVs, and disruptive gene therapy manufacturing. The ShapeTX platform enables pharma innovators to design treatments across a wide range of diseases, including rare genetic disorders as well as debilitating conditions, such as Alzheimer’s, Parkinson’s, and many more. You can find us at shapetx.com and on LinkedIn and Twitter.

At ShapeTX, we are a dynamic team of professionals who are dedicated and passionate about making cures a reality. Through diversity of thought, scientific knowledge, professional rigor and focus we are merging cutting-edge science with extensive drug development expertise to unlock cures to many debilitating diseases.

Shape Therapeutics is headquartered in Seattle, Washington with a satellite site in Boston, Massachusetts.

ShapeTX is seeking an Associate Scientist/Senior Research Associate, Downstream Development. In this role, you will develop and implement viral vector purification processes as part of ShapeTX’s novel gene therapy technology platform.  The Associate Scientist, Downstream Development will be responsible for helping to develop purification unit operations, and executing chromatography and filtration protocols, supporting a wide range of ShapeTX development and therapeutic opportunities.  This is an exciting opportunity to join a high-growth startup and participate in product development for a pioneering RNA targeting technology to create the next generation of gene therapies. The successful candidate will be detail oriented, have a collaborative spirit, and a desire to work in a fast-paced startup

What You’ll Do:

• Perform purifications to support P&PD activities
• Participate in the development of purification unit operations
• Independently follow established protocols, analyze and communicate results
• Maintain laboratory supplies and reagents
• Keep organized and detailed records using an electronic laboratory notebook

What you Bring:

Qualifications:

• Master’s degree in Chemical Engineering, Biochemistry, Chemistry, or a related discipline and  0-2 years of industry experience OR a Bachelor’s degree in Chemical Engineering, Biochemistry, Chemistry, or a related discipline with 2-4 years of industry experience.

Skills and Experience:

• Experience with chromatography and chromatographic instruments
• Experience in the development and optimization of purification processes
• Ability to troubleshoot and think critically
• Strong work ethic and attention to detail
• Ability to multitask and support multiple projects simultaneously
• Ability to work collaboratively in a team-science environment
• Ability to think creatively and tackle challenges with a problem-solving attitude
• Excellent written and verbal communication skills

Preferred Qualifications:

• Experience with AAV production

Compensation & Benefits 

ShapeTX offers a robust benefits package, including but not limited to: Medical, Dental and Vision coverage for employees and their eligible dependents. We provide eligible employees with 12 paid Holidays plus a one week winter break at year end. We are proud to offer a competitive paid parental leave benefit, an annual employee stipend for employees to use however they choose, a Flex Paid Time Off program (allowing flexible PTO for vacation, sick leave, and other purposes) and Company paid Long Term Disability. Employees are eligible to enroll in our Company’s voluntary 401k plan, voluntary Life/AD&D and Voluntary FSA’s.

Pay Range

The salary range for the Associate Scientist role is $82,000 - $110,000 and the salary range for the Senior Research Associate role is $72,000-$98,000. The hired applicant's placement within the range is based on qualifications and professional experience. Additional compensation may include annual target bonus and/or sign-on bonus, equity grant and relocation bonus.

We aspire to Shape Life! not only through our science, but also through our commitment to foster an inclusive environment that supports diverse perspectives and experiences.