Bioinformatics Scientist/Engineer

Belharra Therapeutics · San Diego, CA

Company

Belharra Therapeutics

Location

San Diego, CA

Type

Full Time

Job Description

WHO WE ARE

Belharra Therapeutics is an early-stage small molecule discovery company founded by pioneers in the field of chemical biology. Through the application of our proprietary chemoproteomics platform merged with innovative biology and medicinal chemistry, we are modulating protein function in previously unidentified ways to push the limits of drug discovery. Our aim is to deliver transformative, first-in-class medicines for patients suffering from the most serious diseases. 

WHAT WE ARE LOOKING FOR

We are seeking an exceptional bioinformatics scientist to join our informatics team. Belharra’s informatics team is empowered to make large impacts across the organization and substantially contribute to the discovery and development of interventions for challenging human targets implicated in disease.

WHAT YOU’LL BE RESPONSIBLE FOR

  • Perform computational analysis of mass-spectrometry based proteomics data, with an emphasis on cheminformatics and structural biology.
  • Ability or desire to learn proteomics and apply machine learning models with chemoproteomic datasets.
  • Assist with development of machine learning models for accelerating drug discovery.
  • Work closely with teams (biology, chemistry, proteomics) across the company to help them develop experiments and to analyze, explore, and understand complex data.
  • Deliver actionable insights driving the development of transformative, first-in-class medicines.
  • Clearly and accurately document work and effectively utilize version-control systems.
  • Perform under tight timelines and work effectively across multiple projects and align with different project teams.

WHAT YOU’LL BRING TO THE TEAM

  • MS or PhD in biology, bioinformatics, cheminformatics, structural biology, data science, or related quantitative field
  • Experience with cheminformatics and structural biology (docking, virtual screening, or molecular dynamics)
  • General understanding of small molecule drug discovery.
  • Excellent programming ability with experience applying computational methods to analyze complex biological data.
    • Fluency in Python and its scientific programming ecosystem (Pandas, SciPy, matplotlib, scikit-learn, RDKit, etc)
    • Ability to write maintainable, testable, and well-organized code that is checked into version control systems.
  • Desire to continuously learn and step outside of one’s comfort zone.
  • Ability to effectively communicate with both bench scientists and executive leadership.
  • Experience using REST APIs and interfacing with public biological knowledgebases.

Desired, but not required: 

  • Understanding of proteomics data 
  • Experience using SQL.
  • Experience with the AWS cloud ecosystem
  • Experience with machine learning
  • Experience with bioinformatics workflow tools

WHAT YOU’LL GET AS PART OF OUR TEAM

  • A collaborative and positive culture  
  • Limitless growth and learning opportunities
  • Commitment to talent and leadership development
    • All Belharrans gain access to the SkillCycle platform and receive the opportunity to work 1:1 with a coach to support their growth and development
  • A chance to make a lasting impact on drug discovery and human health
  • Competitive compensation and company ownership
  • Excellent Medical, Dental and Vision coverage from a broad choice of providers and plans 
    • 100% of premium coverage for employees; up to 95% of premium coverage for eligible dependents
  • 401(k) program with a company sponsored contribution
  • “Take what you need” vacation and sick time off policy
  • 10 annual paid company holidays, plus the last week of December
  • A new office and lab space in San Diego with flexibility and autonomy to do your work how and where you need

Pay Scale Range (CA)

$101,000—$128,000 USD

At Belharra Therapeutics, Inc. pay ranges are subject to change and are assigned to a job based on its level within the company.  Individual pay within that range can vary for several reasons including skills/capabilities, experience, and available budget.

Belharra is committed to being an Equal Opportunity Employer and our policy is to provide equal employment opportunities to all applicants and employees without regard to race, color, creed, religion, sex, sexual orientation, gender identity, marital status, citizenship status, age, national origin, ancestry, disability, veteran status, or any other legally protected status and to affirmatively seek to advance the principles of equal employment opportunity.

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Date Posted

02/15/2024

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