Data Science (Biomarkers) Intern

Who Are We?

Prolaio believes that continuous learning and collaboration can make a significant difference in how heart care is administered. We are creating smarter ways to address heart disease and heart risks by uniting patients care teams and researchers on a secure technology-enabled platform that drives clinical innovation and offers a path towards better patient outcomes.
This is precision cardiology and we know it’s within reach.

What Will You Do?

The Overview

As a Data Science Intern on the Biomarkers Team you will develop and validate advanced machine learning pipelines focused on long term time series analysis. Your primary objective is to leverage Foundational Time Series Models and Transfer Learning - such as adapting models from cardiac arrhythmia ECG detection to extract novel physiological insights from wearable and clinical sensor data. This role is essential for advancing our understanding of patient health by translating raw signal data into validated digital biomarkers.

The Specifics

• Model Development & Transfer Learning: Test existing and fine-tune deep learning architectures for time series data specifically utilizing transfer learning techniques to adapt pre-trained ECG-based cardiac models for new physiological signal tasks.
• Signal Processing Pipeline: Build and optimize Python-based signal processing workflows to handle noisy real-world sensor data including filtering feature extraction and artifact removal.
• Foundational Model Implementation: Research and implement emerging foundational time series models to evaluate their zero-shot or few-shot performance on proprietary longitudinal cardiac datasets.
• Validation & Benchmarking: Design rigorous validation frameworks comparing model outputs against a clinician-verified "ground truth" to establish metrics like Mean Absolute Error (MAE) and Intraclass Correlation (ICC).
• Codebase Delivery: Maintain a clean documented and reproducible code repository that transforms raw high-frequency signals into structured analysis-ready biomarker datasets.

Why Prolaio?

• Impactful Work: You will join in the fight against heart failure (HF) and hypertrophic cardiomyopathy (HCM) with the goal of extending and saving the lives of our patients while also being at the forefront of changing the healthcare industry through technology.
• Innovative Environment: You will be part of an organization doing something that’s never been done before.
• Professional Growth: You will join a growing team and have a substantial impact on our daily and future operations with the opportunity to continuously learn and grow.
• Collaborative Team: You will be part of a team of collaborative curious and committed individuals focused on the collective good inclusiveness scientific excellence and advancing digital health for cardiology.

Who You Are?

• Academic Background: Currently enrolled in a Master’s or PhD program in Data Science Electrical Engineering Biomedical Engineering Computer Science or a related quantitative field.
• Technical Proficiency: Strong proficiency in Python and deep learning frameworks (e.g. PyTorch or TensorFlow) with a specific focus on time series or signal data.
• Signal Processing Expertise: Familiarity with digital signal processing (DSP) techniques such as Fourier transforms wavelet analysis and windowing methods for physiological data.
• Machine Learning Knowledge: Solid understanding of modern ML architectures (CNNs RNNs Transformers) and experience with Transfer Learning or fine-tuning large-scale models.
• Data Handling: Experience working with real-world sensor data handling irregular sampling rates and managing large-scale longitudinal datasets.

Compensation: The expected hourly rate for this internship is $50/hour.

**At this time relocation and housing stipends are not offered for this internship.**

What We Do

Prolaio is a clinical intelligence company dedicated to unlocking continuous predictive and shareable heart data to liberate patients from hospital-based reactive care and accelerate every new therapy. The company was created by cardiologists cardiovascular practitioners and data scientists specifically to address the world’s number one cause of death — cardiovascular disease. By combining scientific rigor with cutting‑edge technology Prolaio aims to transform real‑world heart data into faster discovery today and precision care for functional cures tomorrow.

Why Work With Us

Kardigan and Prolaio were both founded to challenge the status quo in cardiology. If we have any shot at radically reducing the time and cost to develop meaningful new medicines and provide better healthcare access and outcomes for patients we need to fundamentally embrace real-world data and AI-based tools in a way that is fully integrated across

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