Director, R&D Data Systems

About Generate:Biomedicines

Generate:Biomedicines is a new kind of therapeutics company – existing at the intersection of machine learning, biological engineering, and medicine – pioneering Generative Biology™ to create breakthrough medicines where novel therapeutics are computationally generated, instead of being discovered. The Company has built a machine learning-powered biomedicines platform with the potential to generate new drugs across a wide range of biologic modalities. This platform represents a potentially fundamental shift in what is possible in the field of biotherapeutic development.

We pursue this audacious vision because we believe in the unique and revolutionary power of generative biology to radically transform the lives of billions, with an outsized opportunity for patients in need. We are seeking collaborative, relentless problem solvers that share our passion for impact to join us!

Generate:Biomedicines was founded in 2018 by Flagship Pioneering and has received nearly $700 million in funding, providing the resources to rapidly scale the organization. The Company has offices in Somerville and Andover, Massachusetts with over 300 employees.

The Role:

We are seeking a creative and motivated R&D Data Systems Leader to build a next generation data platform that will enable our seamless design-build-test-learn cycle. Generate:Biomedicines is an innovative platform company leveraging Machine Learning to design novel protein therapeutics. This role will be an integral part of building a powerful, integrated data platform that streamlines data flow between wet and dry lab functions, ensures the highest levels of data quality, and empowers scientists to make data-driven decisions. The successful candidate will work closely with scientists from across the organization to understand both platform and program requirements, set a vision for a robust, scalable, and highly automated data platform, and lead a team of engineers to translate that vision into high-quality software that rapidly advances our scientific programs. This role is based in our Somerville, MA office with flexibility for hybrid work.

Here's how you will contribute:

• Design, plan, and lead the development of a highly scalable and flexible assay data management platform, which:
  • Captures and standardizes assay results and experiment context leveraging FAIR data principles
  • Enables optimized experiment design
  • Integrates with automation for high-throughput data generation
  • Produces training-ready data for rapid model development 

• Plan, architect, and lead development of data pipelines leveraging internal and external data sources 
• Maintain deep technical understanding of Generate’s data inventory, and design systems to support scientists’ access to data 
• Design and lead implementation of data models to support lab and ML workflows 
• Work with lab and computational scientists to:
  • Identify needs and opportunities for platform improvement
  • Prioritize, plan, and implement
  • Drive adoption and change management 
• Design and lead development of analytical reports and dashboards 
• Lead, manage, mentor and develop a high-performance team of informatics software engineers 

The Ideal Candidate will have:

• Self-motivated and curious with strong desire to both learn from and teach others 
• Outstanding communication and interpersonal skills 
• Master’s or PhD in Computer Science, Data Science, or related field plus 12 years of experience working in the pharmaceutical or biotech domain 
• Hands-on leader who is passionate about both building great software, and building great teams 
• Deep technical and architectural expertise in data storage, cloud architecture, microservices, etc. 
• Demonstrated excellence in software design and architecture 
• Demonstrated expertise in data management best practices for biological data 
• Experience building and maintaining production data pipelines 
• Deep understanding of cloud technologies (AWS a plus) 

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Generate:Biomedicines is committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.

COVID Safety:

Generate:Biomedicines enforces a mandatory vaccination policy for COVID-19. All employees must be fully vaccinated and have received a booster.  The purpose of this policy is to safeguard the health of our employees, their families, and the community at large from infectious disease that may be reduced by vaccinations.  The Company will make exceptions to this policy if required by applicable law and will consider requests for an exemption from this policy due to a medical reason, or because of a sincerely held religious belief, or any other exemptions that may be recognized by applicable.

Recruitment & Staffing Agencies: Generate:Biomedicines does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Generate:Biomedicines or its employees is strictly prohibited unless contacted directly by the Company’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Generate:Biomedicines and the Company will not owe any referral or other fees with respect thereto.