Principal Associate Scientist/Scientist I: Antibody Immunologist

Who we are looking for:

Vor Bio is seeking a Principal Associate Scientist/Scientist I: Antibody Immunologist to contribute to advancing Vor’s targeted immunotherapy approach. This will involve working within a team environment to execute experimental plans requiring fundamental skills in antibody screening, generation, and functional assessment.

Key areas of responsibility:

• Generate, isolate, and analyze monoclonal antibodies in vitro
• Conduct cell-based assays such as flow cytometry to evaluate antibody binding and surface molecule density in primary cells and model cell lines
• Characterize monoclonal antibody parameters in vitro (such as cytotoxicity, IC50, stability)
• Contribute to experimental design, interpretation of data, and oversee troubleshooting with oversight from senior scientific personnel
• Collaborate internally and with external CRO to generate key data sets
• Generate standard operating procedures, work instructions, test methods, study protocols, and technical reports
• Contribute to presentations and progress reports at regular internal research meetings
• Maintain a clear, detailed laboratory notebook to document all experiments, materials, and findings
• Comply with best safety practices

Qualifications:

• BSc, MSc, or PhD in fields such as biochemistry, molecular biology, immunology, cancer biology, or related discipline is required (title and compensation commensurate with experience)
  - BSc with 6+ years of laboratory experience in an academic or industry setting (industry preferred)
  - MSc with 4+ years of laboratory experience in an academic or industry setting (industry preferred)
  - PhD
• Experience with therapeutic antibody analysis, including high throughput screening assays
• Molecular biology experience including cell transduction protocols (electroporation, lentivirus, lipofectamine, etc.)
• Experience with in vitro cellular assays is critical
• Experience with antibody based cytoxicity assays (e.g. ADCC and ADCP) is a plus
• Experience with murine models is recommended, but not required
• Excellent communication, organization, and technical writing skills
• Strong problem-solving skills and the ability to work independently in a startup environment, while contributing to a collaborative culture in line with Vor’s Core Values
• Immediate availability