Principal Scientist, Immunology

Metagenomi · Other US Location

Company

Metagenomi

Location

Other US Location

Type

Full Time

Job Description

We are hiring a  Principal Scientist, Immunology, in our Cell Therapy division. Reporting to the Vice President, Immunology and Pharmacology, this individual will be responsible for leading our Disease Modeling team.  You will leverage your deep industry and academic experience with human T-cell biology and establish and implement disease models for the selection and/or characterization of our therapeutic candidates.  This role will be based in Emeryville, California.
How you’ll contribute: 

  • Establishing and implementing in vitro and in vivo assays and disease models to support the design, selection, and characterization of engineered cell therapy development candidates
  • Work within a multidisciplinary team creating novel engineered cell therapies that deplete pathogenic cells in autoimmunity or cancer
  • Motivate and lead a cross-functional team of talented Scientists and Research Associates
  • Work collaboratively with key stakeholders to deliver pivotal datasets to support development candidate selection and regulatory approval
  • Prepare accurate and timely data summaries and contribute to the writing of technical study reports, papers, and patent applications
  • Participate and present in meetings with business partners, academic institutions, regulatory agencies, and other institutions.

Must haves: 

  • Ph.D. in Immunology and at least 12 years of postgraduate experience, including at least five years in industry
  • Substantial expertise in human T cell biology, preferably 𝝲𝝳 T cells. Additional knowledge in đťť°đťť± T cells is highly desirable.
  • Experience working with CAR-T cells and/or TCR-T cells 
  • Significant expertise in establishing autoimmune and oncology disease models, preferably in vivo
  • Significant cross-functional leadership experience working and collaborating with other functions
  • Highly organized and able to effectively manage time and workflows, prioritizing short--and long-term goals and deliverables.
  • Ability to react quickly and maintain a calm and thoughtful approach at difficult times.
  • Strong communication and presentation skills, experience representing the company in scientific and other external meetings
  • Highly motivated, high integrity standards, a positive attitude, and a commitment to developing life-saving medicines for patients
  • Extremely organized and able to efficiently manage your time and workflows, including skillfully prioritizing both long-term projects and the day-to-day responsibilities of your team
  • Direct supervisory experience leading teams of Scientists and Research Associates with a track record of recruiting, mentoring, and developing talent
  • Outstanding communication, collaboration, and team leadership skills.

California Pay Transparency Disclosure:

This position is classified as an exempt salaried position under the Federal Labor Standards Act.  The anticipated base salary range for this position will be $185,000 -$200,000.  You will also be eligible to receive equity, bonuses, and a full range of medical, financial, and other benefits depending on the position offered. Please note that individual total compensation for this position will be determined at the Company’s sole discretion and may vary based on location, skill level, years and depth of relevant experience, and education. 

#LI-NG1


About Metagenomi

Metagenomi is a gene editing company committed to developing potentially curative therapeutics by leveraging a proprietary toolbox of next-generation gene editing systems to accurately edit DNA where current technologies cannot. Our metagenomics-powered discovery platform and analytical expertise reveal novel cellular machinery sourced from otherwise unknown organisms. We adapt and forge these naturally evolved systems into powerful gene editing systems that are ultra-small, extremely efficient, highly specific and have a decreased risk of immune response. These systems fuel our pipeline of novel medicines and can be leveraged by partners. Our goal is to revolutionize gene editing for the benefit of patients around the world. For more information, please visit https://metagenomi.co/.


What makes Metagenomi a unique place to work?

  • We are passionate about developing technologies derived from microbial-rich ecosystems that have the power to enable therapeutic development and the potential to cure devastating disease.
  • We have cultivated an amazing culture that values teamwork, curiosity, scientific rigor, and fun. We have a strong commitment to work/life balance, host a weekly employee happy hour and events, provide catered lunches and endless snacks, and more! 
  • We offer competitive compensation including a market-benchmarked salary, annual target bonus potential, pre-IPO equity, and a comprehensive benefits plan, including 401(k) with company matching, a retirement safe harbor plan, and other perks.

At Metagenomi, we know that our people drive our success. We are an equal-opportunity employer and believe in and value diversity and inclusion. Metagenomi provides an open, collegial, and friendly work environment where we empower people and provide them with opportunities to develop their long-term careers. Metagenomi does not discriminate on the basis of race, color, religion, sexual orientation, gender, age, physical or mental disability, or any other status protected under federal, state, or local law. Please note, all candidates must be authorized to work in the United States.


Applicants/Employees have rights under various State and Federal Employment Laws, including

without limitation:


  • Family & Medical Leave Act 

  • Equal Employment Opportunity Commission

  • Employee Polygraph Protection Act 

  • California Family Rights Act 

  • California Fair Employment and Housing Act

Notice to agencies: Our in-house Talent Acquisition Team manages all employment opportunities at Metagenomi. Agencies and independent recruiters must be approved as a vendor by Metagenomi’s Talent Acquisition team. To protect the interests of all parties, Metagenomi will not accept unsolicited resumes, profiles, or biographies. Any unsolicited resumes sent to Metagenomi will be considered referrals and the property of Metagenomi.


Apply Now

Date Posted

09/21/2023

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