Principle Scientist - CPAD

• State of the art knowledge of modern synthetic methodology, including aspects of asymmetric synthesis, green chemistry, catalysis, and physical organic chemistry as it relates to reaction mechanism is expected.
• Contemporary knowledge of drug development, the pharmaceutical industry, and fundamental principles of process development from a laboratory and manufacturing perspective.
• Strong track record of successful delivery of projects, using sound scientific analysis and judgment to advance programs
• Good interpersonal skills
• Experience of leading small teams of 5-8 chemists, mentoring and directing other colleagues.
• Excellent oral and written communication skills, including the ability to maintain an accurate scientific notebook, and draft concise emails, written reports, publications, synthesis information packages and related documents
• Rational, innovative and creative approach to problem solving.
• Job location: Onsite, Chennai
• Lead a group of 5-8 process chemists at an external partner located in India to deliver phase-appropriates processes and vendor synthetic information packages (VSIPs) for Pfizer's Drug-Linker portfolio.
• Use extensive technical knowledge and experience in state-of-the-art organic and process chemistry to develop safe, sustainable, robust, cost-efficient, and phase-appropriate process that are aligned with internal business needs.
• Develop strategic plan to develop and implement purification and separation capabilities at the external partner that is driven by drug linkers portfolio needs with internal stakeholders.
• Work collaboratively and effectively, building and leading high performing teams
• Ensure accurate and timely documentation of experimental work, and clear and concise presentation of work to stakeholders both internally and externally.
• Co-ordinate work with other functions (Process safety, engineering, analytical)/ departments to achieve project objectives.
• Build a strong interface and network with Pfizer's Chemical Process and Analytical Development group (Global Chemical Research and Development) and keep up to date with synthetic and technology advancements.
• Support in designing and refining workflows and metrics.
• Look for opportunities to align, share and implement best practices.
• Contribute to the development of a strong scientific, process chemistry, safety and quality culture within the chemistry labs.
• Master's degree in Chemistry, Chemical Engineering or a related field and 10+ years of experience in process chemistry research and development towards New Chemical Entities (APIs) or fine chemicals
• or
• PhD in Organic Chemistry or a related field with 6+ years of experience in process chemistry research and development towards New Chemical Entities (APIs) or fine chemicals
• Develop state of the art purification strategies and capabilities for complex synthetic molecules such as Drug-Linkers.
• Plan the scientific direction of projects by providing high quality experimental planning, evaluation and characterization of chromatography purification and synthetic processes.

Work Location: Onsite, Pfizer Chennai
Pfizer is an equal opportunity employer and complies with all applicable equal employment opportunity legislation in each jurisdiction in which it operates.
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