R&D Scientist – Assay Developer

About CRISPR QC

CRISPR QC, a spinoff from Cardea (now Paragraf) in San Diego, provides unprecedented interrogative gene editing data on the innovative CRISPR Chip biosensor platform. This biocompatible semiconductor technology swiftly captures and converts each step in CRISPR/Cas-based gene-editing into data. Our biosensors facilitate QC checks on CRISPR/Cas components, such as gRNA design, Cas9 selection, and gRNA-Cas protein kinetics, quickly and cost-effectively. This occurs before transitioning to in-cell genome editing, significantly reducing the risk and costs associated with potential failures. CRISPR Chip tests save time and money, expediting genome-editing efforts in the field.

About the Job

We are currently seeking a motivated and experienced scientist with a strong industrial background in developing molecular tests involving CRISPR/Cas-based gene editing.

Join our rapidly growing R&D team in advancing new applications of CRISPR/Cas-based gene editing for therapeutic development.

A successful candidate will conduct innovative tests using CRISPR-Chips (our proprietary technology) to create new pipeline products (test kits or protocols) supporting CRISPR/Cas-based gene editing for therapeutic applications. There will also be opportunities to lead teams, advance your career at the intersection of gene editing and the Internet of Biology (digital presentation of biological reactions on biosensors and remote data analysis) and demonstrate leadership in bringing test products to market.

Responsibilities: 

• Plan and execute various laboratory activities on CRISPR-Cas gene editing tests, aligned with the R&D team and the company’s main goals
• Develop creative solutions to obstacles that arise during the product development process
• Interface/interact with key stakeholders from the R&D team and other departments (data analysis, customer service, and business development, etc.) on new test products
• Interact with external industrial collaborators (from the therapeutic world) and lead the development of tests for the contract projects
• Perform data analysis; write study reports and SOP, update test results and present project assessments to both internal and/or external stakeholders (industrial collaborators) 
• Supervise and provide daily technical guidance to junior scientists in the lab (team) 

Qualifications: 

• Ph.D. training in relevant scientific disciplines (Biochemistry, Molecular Biology, Cell Biology, etc.), knowledge and work experience in any of these areas (biosensor, bioinformatics, computational biology, machine learning) are a big plus
• 5+ years of post-graduate experience with expertise in activities including development of molecular tests involving CRISPR/Cas9-based gene-editing, either in vitro or in cell, mostly relating to animal cell models  
• Familiarity with the process of molecular biology test development, test documentation (SOP writing) and test product transfer (to production or collaborators) 
• Experience with laboratory automation including operating robotic liquid handlers a plus
• Ability to think and work both independently and collaboratively in a multidisciplinary team environment
• Ability to communicate and present effectively with internal and external stakeholders both verbally and in writing. 

 
Additional Information: 
CRISPR QC is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin.  

 
CRISPR QC is not accepting unsolicited assistance from search firms for this employment opportunity. All resumes submitted by search firms to any employee at CRISPR QC via-email, the Internet or in any form and/or method without a valid written search agreement in place for this position will be deemed the sole property of CRISPR QC. No fee will be paid in the event the candidate is hired by CRISPQ QC as a result of the referral or through other means.