Research Associate II

WHAT WE ARE LOOKING FOR

Belharra is seeking a motivated Research Associate II to join our Proteomic team and develop and support a robust chemoproteomic platform.  In this role, you’ll collaborate with chemists and biologists to create and use chemical tools to enable drug discovery.  The successful candidate will have a background with high-throughput proteomic sample preparation and expertise in mass spectrometry.  This role will contribute to the growth of Belharra’s research portfolio by screening our chemical probe library to identify and characterize interactions with proteins of interest in a variety of cell-based assays.  Belharra is a highly engaged and collaborative environment, and we are seeking likeminded colleagues. 

WHAT YOU’LL BE RESPONSIBLE FOR

• Collaborate with the proteomics team to implement our high throughput chemoproteomic platform. This platform is based in live cells and combines a library of chemical probes with quantitative mass spectrometry.
• Enable automated systems for preparing proteomics samples, including chemical probe enrichments, activity-based proteomics, MS-based quantities strategies (TMT, SILAC, DIA).
• Prioritize tasks to support multiple and parallel projects.
• Manage tissue culture demands (including multiple cancer cell lines and primary cell models).
• Basic understanding of mass spectrometry-based software (Proteome Discover, Skyline).

WHAT YOU’LL BRING TO THE TEAM

• Bachelor’s degree with 2-6 years of experience or master’s degree with 0-3 years of experience in fields like chemical biology, biochemistry, or cell biology (industry experience is a plus).
• Hands-on experience with molecular biology techniques (SDS-PAGE, western blotting), cell culture, and proteomic sample preparation.
• Familiarity with high-throughput or automated assays.
• Basic knowledge of characterizing small-molecule and protein identification.
• Understanding of proteomics sample processing
• Familiarity with small-molecule pharmacology, chemical biology, and basic chemical principles is advantageous.
• Strong troubleshooting and problem-solving abilities.
• Attention to detail and good documentation practices.
• Excellent oral and written communication skills.
• Proficient in Microsoft Office applications.
• Ability to work both independently and as part of a team in a fast-paced learning environment.
• A strong team player that enjoys drug discovery and making a meaningful impact to drive projects forward.

Physical Demands

• Lifting of 20-30 pounds of equipment.

WHAT YOU’LL GET AS PART OF OUR TEAM

• A collaborative and positive culture  
• Limitless growth and learning opportunities
• Commitment to talent and leadership development
  • All Belharrans gain access to the SkillCycle platform and receive the opportunity to work 1:1 with a coach to support their growth and development
• A chance to make a lasting impact on drug discovery and human health
• Competitive compensation and company ownership
• Excellent Medical, Dental and Vision coverage from a broad choice of providers and plans 
  • 100% of premium coverage for employees; up to 95% of premium coverage for eligible dependents
• 401(k) program with a company sponsored contribution
• “Take what you need” vacation and sick time off policy
• 10 annual paid company holidays, plus the last week of December
• A new office and lab space in San Diego with flexibility and autonomy to do your work how and where you need