Research Associate, Process Development
Job Description
Vizgen, Inc. – Cambridge, MA
Vizgen is a rapidly growing company developing the next generation of spatially resolved genomic profiling tools that enable researchers to gain new insight into the biological systems that underlie human health and disease. The company's groundbreaking MERFISH spatial transcriptomics technology images RNA molecules with high accuracy and unrivaled detection efficiency at subcellular resolution. MERFISH provides transformative insight into a wide range of tissue-scale basic research and translational medicine in oncology, immunology, neuroscience, infectious disease, developmental biology, and regenerative medicine. For more information, go to www.vizgen.com
Position Summary:
We are seeking a highly motivated Research Associate to work on the development of cutting-edge products and reagents for the rapidly evolving spatial-omics field. The Research Associate will work within the Process Development group (R&D) and will also contribute in cross-functional team projects for successful process development and transfer of products and reagents to Operations. The successful candidate will work hands-on to execute antibody-oligo conjugation reactions, qPCR, centrifugation, ultrafiltration/diafiltration, enzyme kinetic reactions and other standard unit operations. A high degree of flexibility, creativity and initiative is essential for success. Strong technical, organization, communication, inter-personal, and trouble shooting skills are essential.
Key Responsibilities:
- Work within Process development (R&D) group to generate, analyze and present process data to support commercialization of reagents, consumables and kits for latest spatial transcriptomic and spatial-omics platforms and accompanying workflows.
- Independently design and execute experiments to study and optimize process parameters for development of reagents and consumables.
- Contribute towards the development of appropriate quality control methods for the evaluation and testing of reagents and consumables.
- Contribute towards the development of data packages for transfer of new processes to operations.
- Execute experiments that involve commercialization of benchtop methods and techniques for Vizgen’s MERFISH technology.
- Author technical reports of process characterization and optimization.
Requirements and Qualifications:
- B.S. or M.S. in Chemical Engineering, Biological Engineering, or equivalent degree in life sciences.
- 0-2 years experience in biotechnology/pharma industry.
- Experience and/or familiarity of correct operation of basic laboratory equipment: pH meters, DO probes, lab scales, centrifuges, chemical fume hoods is required.
- Experience and/or familiarity in the use of analytical equipment such as spectrophotometers, microscopes, plate readers, and flow cytometers is preferred.
- Experience in enzyme kinetics, qPCR, antibody-oligo conjugation is a plus.
- Knowledge and/or experience in process characterization, process optimization is a plus.
- Experience in design of experiments and in the use of statistical tools and techniques (JMP) is a plus.
- Demonstrated knowledge of molecular biology, cell biology and imaging protocols (fluorescent in situ hybridization (FISH), immunofluorescence, immunohistochemistry, fluorescent microscopy, single-molecule imaging, flow cytometry, cell culture, tissue sectioning, NGS library construction, RNA-seq, cell transfection, antibody-labeling, etc.) is a plus
- Ability to work independently as well as part of results-oriented cross-functional project teams
- Ability to collaborate and present experimental work to cross-functional groups
- Must have strong analytical, problem solving, planning and organizational skills
If you aren't sure you meet every requirement but are excited about what you read here, please consider applying! We believe diversity drives innovation. Above all, we're looking for the right person with skills and talent to grow the company together all while enriching your professional and scientific experience.
We offer a competitive salary, meaningful stock ownership, 401K, health benefits, a great work environment and the opportunity to enter a high-growth startup company. We are recruiting candidates who have demonstrated leadership and excellence throughout their careers and are excited by the prospect of tackling challenging technical problems.
This position may be subject to pre-employment checks, including driving history check, drug screening and a background check for any convictions directly related to its duties and responsibilities. All pre-employment checks will comply with all applicable federal, state, and local laws.
WE ARE AN EQUAL OPPORTUNITY/AFFIRMATIVE ACTION EMPLOYER
Vizgen affords equal employment opportunity to all qualified persons regardless of race, color, religious creed, national origin, age, military status, sexual orientation, disability, genetic information, gender identity, gender expression or gender unless based upon a bona fide occupational qualification.
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Date Posted
11/17/2023
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10
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