Research Associate/Senior Research Associate, Process Development

Role Summary

Reporting to the Director, Process Development, this position will be responsible for developing and optimizing the production of AAV therapeutic candidates in the lab, with collaborators, with the goal of advancing the development of novel targets for cardiac and neurodegenerative disorders. As an early hire at a new company, you will have exposure to senior management, and you will be influential in championing and developing Lexeo’s culture. You will have an opportunity to learn in a fast-paced startup company, while working collaboratively within a multidisciplinary team that is dedicated to the development of new therapies.

Location

Lexeo Office. New York, NY

Primary Responsibilities

• Develop bioreactor-based cell culture processes for manufacturing of AAV-based gene therapy vectors across multiple programs
• With guidance, optimize expression and harvest processes for improved consistency, performance, and product quality
• Support scaleup and process transfer to manufacturing groups; including scale down experiments, and authorship of technical documents
• Plan and prepare for reliable execution of experiments, including maintaining inoculum cultures, ensuring availabilities of reagents, and preparation of equipment
• Coordinate experiment activities within department, including purification and analytical teams
• Evaluate new and emerging technologies as they relate to cell culture processes
• Analyze and document experimental data in electronic laboratory notebooks in a timely and accurate manner in accordance with the company quality management system
• Present scientific data to colleagues at internal meetings

Required Skills & Qualifications

• BS/MS degree with 0-2+ years of relevant experience in Chemical Engineering, Biomolecular Engineering, Biomedical Engineering, Biotechnology, Biochemistry, Microbiology, or related fields
• Hands-on experience with cell culture 
• Solid understanding of aseptic technique
• Enthusiastic learner with an attention to detail
• A demonstrated knowledge of and interest in cell biology
• Ability to design scientifically sound experiments under guidance, to interpret results, and to present findings
• Effective written and oral communication skills

Depending on qualifications and overall experience, base salary is likely to be $75,000-$90,000 per year.

Lexeo Therapeutics is an EEO employer committed to an exciting, diverse, and enriching work environment.