Scientist 1/2 - Analytical Immunology

About Affinivax

Affinivax is a Cambridge-based clinical-stage biotechnology company with a novel, next-generation approach to the development of vaccines and immunotherapies targeting infectious and other immune-mediated diseases. This novel and highly efficient vaccine technology – called Multiple Antigen Presenting System (MAPS) – enables the high-affinity binding of protective polysaccharides as well as proteins in a single vaccine, uniquely inducing a broad and protective B-cell and T-cell immune response.
Our vision is to take a major step forward in vaccine innovation to prevent and combat a wide range of infectious and other immune-mediated diseases, protecting infants and adults in our communities and making a meaningful impact on global public health. Affinivax is focused on developing vaccines for the most challenging bacterial infections, with a goal of improving upon existing vaccines and providing solutions for where there are no vaccines or prevention strategies available today.

The role…

Affinivax is currently seeking a highly motivated scientist to use his/her expertise in assay development. The Analytical Immunology Team at Affinivax is responsible for the development and qualification of assays to support IND-enabling toxicology studies and clinical trials. This position is ideally suited for someone with prior immunoassay development and qualification experience.

You will have the opportunity to…

• Lead, design, develop, qualify, and implement ligand-binding assays to support early and late-stage vaccine development programs.
• Align priorities to the entire program development strategy; supervise the day-to-day laboratory activities, identify potential issues, and deliver high-quality data within defined timelines.
• Troubleshoot method and instrumentation problems; be proactive in solving technical issues.
• Author, review, and approve SOPs, study protocols, reports, and other scientific and quality documents.
• Present scientific data to colleagues in group meetings and prepare and present internal and external presentations.
• Present progress updates to senior management.

Who you are and what you bring to the team…

• Ph.D. (Biochemistry, Immunology, or related discipline) with 1-4 years of post-graduate experience or Master’s degree (Biochemistry, Immunology, or related discipline) with 10+ years of post-graduate experience
• Industry GXP experience preferred.
• Extensive hands-on working experience with analytical assay development and qualification - expertise in multiplex (Luminex and MSD) based immunoassay development is a plus
• Experience in other analytical methods, such as cell-based and biochemical assays, is a plus
• Experience in running stability protocols with associated experimental planning and data collection and analysis
• Data processing skills using Windows-based software (Excel, GraphPad Prizm, JMP, etc.)
• Strong ability to multi-task and willingness to work effectively in a highly collaborative and diverse environment as a team player with a strong work ethic
• Able to maintain written records in the form of laboratory notebooks
• Strong written and oral communication skills

What We Offer:

• Competitive compensation
• Medical and Dental plans (BCBS), employer-paid at 85%
• Vision Insurance, employer-paid at 100%
• Life Insurance, Short- and Long-Term Disability
• Flexible Spending Accounts/Health Savings Accounts
• Wellness Benefits
• 401(k) Plan with a 4% match
• Tuition Reimbursement
• Generous PTO package
• 11 paid holidays, plus Holiday Shutdown
• Pet Insurance
• Subsidized Parking
• Commuter Reimbursement Program
• Brand new facility in Kendall Square

Please Note:
In accordance with Affinivax’s duty to provide and maintain a safe workplace that is free of known hazards, we have adopted a COVID-19 vaccine policy to protect the health of our employees and their families, our visitors, and the community at large from COVID-19. This policy requires all employees, contractors, and temporary workers, to (1) obtain an approved vaccination and provide proof of vaccination or (2) request an accommodation for a medical or religious exemption. Our policy is based on guidance from the Centers for Disease Control (CDC) and Prevention.

Affinivax is committed to providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, national origin, age, disability, genetic information, status as a veteran or as a member of the military or status in any group protected by applicable federal or state laws.

Agencies:
All resumes submitted by search firms/employment agencies to any employee at Affinivax via email, the internet, or in any form and/or method will be deemed the sole property of Affinivax, unless such search firms/employment agencies were engaged by Affinivax for this position and a valid agreement with Affinivax is in place. In the event a candidate who was submitted outside of the Affinivax agency engagement process is hired, no fee or payment of any kind will be paid.