Scientist, NGS

Programmable DNA, the software of Life, is finally here! Twist Bioscience is developing a disruptive Synthetic DNA technology that will change the world, enabling widespread health and sustainability. Synthetic biologists will use our products to engineer how organisms produce cures to diseases, make everyday chemicals by using the atmosphere as the carbon source, enable plants to make their own fertilizers, and to create in-vivo diagnostics that alert us when we are sick, and many more applications.

We are looking for an outstanding Scientist, NGS to join our R&D team. The scientist will support R&D efforts in developing custom DNA-based applications and assays for Next-Generation  Sequencing Targeted Enrichment products. The ideal candidate will be driven and willing to learn new techniques. This position will design and perform experiments, collect and analyze data for the development of NGS products and applications. The ideal candidate will be familiar with developing and optimizing commercial kits and/or kit components including formulation and protocols. This position will interact closely with bioinformaticians on data analysis  and other key groups across the Twist organization. 

What You’ll Be Doing

Support research and development (R&D) efforts to create custom DNA-based
applications and tests for next-generation sequencing (NGS) targeted enrichment products.
Design and conduct experiments, collect and analyze data to develop NGS products and applications.
Create and improve commercial kits and/or kit components, including formulations and protocols.
Work closely with bioinformaticians on data analysis and other functional groups within the organization, such as the product development team. Follow regulatory requirements and ISO 13485 standards

What You’ll Bring to the Team

A Master's degree with 3 years of experience or a PhD with 1 year of post-graduate experience in a related field such as molecular biology, biochemistry, genetics, genomics, or chemistry. Experience in an NGS company is highly desirable.
Strong knowledge of NGS methods, products, and applications.
Hands-on experience with large-scale genomic methods such as whole genome
sequencing, exome sequencing, target enrichment, RNA sequencing, and single-cell
sequencing.
Experience with NGS library preparation methods.
Understanding of bioinformatics and bioinformatics tools, including genome alignment,
mapping, variant calling, and annotation. Ability to perform basic analysis and
communicate needs with bioinformaticians.
Proficiency in molecular biology techniques including DNA purification, DNA
quantification, and PCR.
Excellent documentation and communication skills, including proficiency in written and spoken English.
Strong interpersonal skills and the ability to work well in a team.
Attention to detail and the ability to work efficiently in a fast-paced environment.

● Experience developing products for commercial launch

● Coding skills in R, Python or equivalent languages
● Experience with liquid handling systems and automation

About Twist Bioscience

Twist Bioscience synthesizes genes from scratch, known as “writing” DNA. Just as children learn to both read and write, the next phase of development for the genomics revolution is the ability to write DNA.

At Twist Bioscience, we work in service of people who are changing the world for the better. In fields such as health care, agriculture, industrial chemicals and data storage, our unique silicon-based DNA Synthesis Platform provides precision at a scale that is otherwise unavailable to our customers.

Twist Bioscience Corporation is an Equal Opportunity Employer. Twist Bioscience Corporation provides equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, genetic characteristics, or any other category protected by law.

San Francisco applicants: Pursuant to the San Francisco Fair Chance Ordinance, we will consider for employment qualified applicants with arrest and conviction records.

The base cash compensation for this California-based role is targeted at $101,000 - $123,500+ bonus + equity + benefits. Final compensation amounts are determined by multiple factors, including candidate skill, experience, expertise, and location and may vary from the amount listed above. Compensation may be different in other locations."

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