Scientist, Protein Science

The Role:

We are looking for a researcher with a strong background in protein science to support our therapeutic programs and to improve our technology discovery platform. We are seeking curious, enthusiastic, competent, and self-motivated individuals to work in our company. 

Here’s What You’ll Do:

• Execute protein production and purification procedures of RNA guided nucleases
• Troubleshoot and improve protein production and purification procedures of new fusion proteins based on RNA guided nucleases
• Construct library plasmids and assist protein engineering projects
• Work as part of a multi-disciplinary team to identify and optimize new genome editing systems
• Analyze experimental results and communicate data at team research meetings
• Contribute to publications and patent applications
• Follow advancements in the field of gene editing and gene therapy published in the literature and presented at conferences

 Requirements:

• PhD in Biochemistry, Chemistry, Molecular Biology, or a related field or BA/BS/MA/MS with 7+ years of experience in a related field
• Experience with protein expression and purification, including experience developing or troubleshooting purification procedures and protein solubility is required
• Hands-on experience using AKTA FPLC systems and Unicorn software (or similar systems and software) is highly preferred.
• Hands-on experience constructing plasmids and/or library plasmids using Gibson assembly, error-prone PCR and/or site saturation mutagenesis  is highly preferred;
• Experience enzymatic/kinetic assay and protein-protein/protein substrate interaction is preferred
• Experience with analytical techniques for proteins and nucleic acids such as UV-Vis, SDS-PAGE, HPLC and endotoxin measurement.
• Relevant technical skills for data analysis, DNA and protein sequence analysis, ELN documentation, and presenting results.
• Strong oral and written communication skills

We’re committed to finding the best ways to support our teams so they can do their best work. We take care of our employees, right from the start.

Health & Wellness

• Medical, vision, and dental insurance covered at 90%
• Low deductible, no co-insurance and no copays for mental health visits (for in-network care)
• Annual fitness reimbursement
• Employer paid for access to wellness apps and programs like Task Human

Financial

• Competitive compensation
• 401(k) retirement plans with a 4% employer match and no vesting period
• Employer-paid life insurance and short- and long-term disability insurance
• Employer-sponsored flexible spending accounts (FSA) and dependent care account (DCA)
• Access to a 1-on-1 financial advisor
• Commuter reimbursement benefit
• Monthly cell phone stipend

Time Off & Flexibility

• Unlimited paid time off, including vacation, sick leave, family leave, personal days, and bereavement
• 18 paid company holidays, plus an end-of-year holiday shut down
• 12 weeks of parental leave
• Federal Family and Medical Leave Act (FMLA) and Massachusetts Paid Family and Medical Leave (PFML), administered by Unum

Development Journey

• Insights Discovery training for every employee to make the most of workplace relationships
• Ongoing professional development, including manager training
• Access to LinkedIn Learning, a self-guided online education platform