Scientist, Spatial Genomics

Who We Are:

Calico (Calico Life Sciences LLC) is an Alphabet-founded research and development company whose mission is to harness advanced technologies and model systems to increase our understanding of the biology that controls human aging. Calico will use that knowledge to devise interventions that enable people to lead longer and healthier lives. Calico’s highly innovative technology labs, its commitment to curiosity-driven discovery science, and, with academic and industry partners, its vibrant drug-development pipeline, together create an inspiring and exciting place to catalyze and enable medical breakthroughs.

Position Description:

Calico is seeking a talented Scientist for our Genomics Technology Lab, passionate about teamwork and emerging technologies. Our lab utilizes advanced technologies, including single-cell and spatial profiling, to tackle challenging biological questions. In this role, you will serve as both an experimental and computational expert, optimizing workflows, analyzing emerging data, and pushing current technologies and computational algorithms to the cutting edge. Your contributions will directly support Calico’s mission to enhance human healthspan and lifespan. 

Responsibilities:

• Designing, conducting, analyzing and interpreting hands-on experiments
• Collaborating closely with our machine learning and image analysis groups
• Innovating our single-cell and spatial transcriptomics methods to improve data interpretation and result quality

  Position Requirements:

• PhD in Molecular Biology, Genetics, Genome Sciences, Bioengineering, Bioinformatics, or related fields
• Hands-on laboratory NGS experience
• Familiarity with spatial and single cell genomics workflows (Nanostring, Vizgen, Xenium, SMART-seq, Scale, Parse, etc.)
• Strong bioinformatics skills with substantial experience in genomic data analysis using R and/or Python
• Must be willing to work onsite five days a week

Nice To Have:

• Experience working with cell culture
• Experience with tissue processing and handling
• Experience with cryostat and/or microtome & histology techniques 

The estimated base salary range for this role is $127,000 - $135,000. Actual pay will be based on a number of factors including experience and qualifications. This position is also eligible for two annual cash bonuses.