Scientist/Senior Scientist

About Voyager

 Voyager Therapeutics (Nasdaq: VYGR) is a biotechnology company dedicated to breaking through barriers in gene therapy and neurology. The potential of both disciplines has been constrained by delivery challenges; Voyager is leveraging innovative expertise in capsid discovery and deep neuropharmacology capabilities to address these constraints. Voyager’s TRACER AAV capsid discovery platform has generated novel capsids with high target delivery and blood-brain barrier penetration at low doses, potentially addressing the narrow therapeutic window associated with conventional gene therapy delivery vectors. This platform is fueling alliances with Pfizer Inc., Novartis and Neurocrine Biosciences as well as multiple programs in Voyager’s own pipeline. Voyager’s pipeline includes preclinical programs in Parkinson’s disease, Alzheimer’s disease, and amyotrophic lateral sclerosis (ALS), each with validated targets and biomarkers to enable a path to rapid potential proof-of-biology. For more information, visit www.voyagertherapeutics.com

Scientist/Senior Scientist

We are currently seeking an experienced and highly motivated Scientist/Senior Scientist who shares our passion for the promise of gene therapy. The successful candidate will work with our multidisciplinary team in Cambridge, Massachusetts. This is an ideal position for a candidate with a strong background in preclinical non-human primate (NHP) experiments, who thrives in a team-oriented, fast-paced, and cross-disciplinary start-up biotech environment.

The candidate will contribute to the design and execute NHP studies to support platform and discovery research. The successful candidate will interact with cross-functional capsid discovery and research program teams to execute in vivo pharmacology, biodistribution, PK/PD, and toxicology studies using AAV-based gene therapy approaches. The candidate will also perform quality control and analyze study data, and communicate study progress through presentations and reports.

Responsibilities

· The candidate will contribute to experimental design, execution, and data analysis for NHP studies that support Voyager’s platform and therapeutic programs.

· Responsibility as a study monitor to review study protocols and address requests/questions from external collaborators and CROs

· Coordinate with capsid discover team, therapeutic program leads, and operations to set up studies aligned with project requirements and timelines.

· Monitor study progress and coordinate study activities, such as shipping and receiving of test article and tissue samples

· Travel and monitor in-life studies at CRO sites and report site-visit results to Voyager teams

· Maintain and update key events in study log and database and timely communicate study status to program teams

· Review study report, perform data analysis and present study results as needed

Requirements

· Education: A PhD degree in Pharmacology, Biology or a relevant discipline, with a minimum of 2 years of experience OR a master’s degree with 5 years of experience OR a bachelor’s degree with 8 years of experience

· Experience of working with large animals, ideally with NHPs

· Familiar with in vivo techniques, preferably hands-on experience in dosing and blood/sample collections; willing to learn new techniques if needed

· Competency with database, spreadsheet and presentation applications (eg. Excel, PowerPoint, Smartsheet, Data entry systems, or similar)

· Outstanding problem-solving skills and ability to manage multi-tasks at the same time.

· Prior experience with study protocol generation and study design is preferred

· Prior experience in neuroscience is preferred

· Self-motivated, able to work independently, highly organized with strong attention to details