Senior Associate Scientist, Antibody Engineering

Job Description

About This Role

HI-Bio, Inc., a Biogen company is seeking a highly motivated Senior Associate Scientist (SAS) with a background in antibody engineering to drive the discovery and validation of novel therapeutic targets in autoimmune and inflammatory diseases.

What You Will Do

• Directly contribute to the workflow for antibody construct design, expression, and purification to support discovery programs. 
• Perform assays to assess biophysical properties, developability and basic in vitro biological function to characterize antibody drug candidates and support lead selection and optimization.
• Contribute to outsourcing of plasmid construction and protein characterization and manage CROs as needed to complement in-house workflows.
• Contribute to HI-Bio discovery programs by developing novel and innovative therapeutic strategies to address autoimmune and inflammatory diseases.

This position is Hybrid based and travel to our San Francisco office on a regular basis. Candidates must be within a commutable distance to be considered.

Who You Are

You are an enthusiastic scientist eager to push antibody drug discovery programs from the bench into clinical testing. You are driven by the opportunity to play a key role in multiple target discovery programs.

Qualifications

Required Skills

• Bachelors or Masters degree in biology, biochemistry, chemical engineering, or related scientific field with 2-4 years of Pharmaceutical or Biotech industry experience.
• Hands-on experience with protein expression, and purification from mammalian cell culture is required.
• Demonstrated track record of independent critical thinking and scientific achievement in protein sciences as demonstrated by publications, patents, or pipeline contributions.

Preferred Skills 

• Experience with research-stage biophysical characterization for developability and/or basic assay development with in vitro cellular assays using cell lines or primary cells is preferred.
• Familiarity with bispecific antibody design and characterization, mast cell biology or immune mediated diseases is considered a plus.

Additional Information

HI-Bio, Inc. is a Biogen company based in South San Francisco, California. As of July 2, 2024, we are part of Biogen’s global team, with a commitment to excellence and a pioneering spirit. As part of a mid-sized biotechnology company, we offer the stability and resources of a well-established business while fostering an environment where individual contributions make a significant impact. Our team encompasses some of the most talented and passionate achievers who have unparalleled opportunities for learning, growth, and expanding their skills. Above all, we work together to deliver life-changing medicines, with every role playing a vital part in our mission: Caring Deeply, Achieving Excellence, Changing Lives. 

Our team in San Francisco is specifically focused on transforming the lives of patients with severe immune-mediated diseases by developing novel targeted therapies with outsized clinical impact, faster. To accomplish this, we are seeking top talent to join us on our journey. 

The base compensation range for this role is $72,200 - $97,500. Base salary is determined by a combination of factors including, but not limited to, job related years of relevant experience, internal equity, and location of the job. Additionally, this role is eligible for participation in Biogen’s LTI grants and other incentive programs. Biogen offers a full range of benefits that include medical, dental, life, long and short-term disability insurances, vacation, end-of-year shutdown, and 401K participation and matching contributions.

Why Biogen?

We are a global team with a commitment to excellence, and a pioneering spirit. As a mid-sized biotechnology company, we provide the stability and resources of a well-established business while fostering an environment where individual contributions make a significant impact. Our team encompasses some of the most talented and passionate achievers who have unparalleled opportunities for learning, growth, and expanding their skills. Above all, we work together to deliver life-changing medicines, with every role playing a vital part in our mission. Caring Deeply. Achieving Excellence. Changing Lives.

At Biogen, we are committed to building on our culture of inclusion and belonging that reflects the communities where we operate and the patients we serve. We know that diverse backgrounds, cultures, and perspectives make us a stronger and more innovative company, and we are focused on building teams where every employee feels empowered and inspired. Read on to learn more about our DE&I efforts.

All qualified applicants will receive consideration for employment without regard to sex, gender identity or expression, sexual orientation, marital status, race, color, national origin, ancestry, ethnicity, religion, age, veteran status, disability, genetic information or any other basis protected by federal, state or local law. Biogen is an E-Verify Employer in the United States.