Senior Clinical Project Manager

This position is posted by Jobgether on behalf of a partner company. We are currently looking for a Senior Clinical Project Manager in the United States.

This role offers the opportunity to lead complex, high-impact clinical research projects across global and regional studies within a fast-growing, quality-driven clinical research environment. You will oversee end-to-end project execution across multiple phases of clinical trials, ensuring alignment between sponsors, internal teams, and external vendors. Acting as a key point of coordination, you will guide cross-functional teams through study start-up, execution, and close-out while ensuring timelines, budgets, and regulatory requirements are met. The position combines strategic oversight with hands-on project leadership, including risk management, financial tracking, and client communication. You will work closely with scientific, operational, and regulatory stakeholders to drive study success and operational excellence. This is a highly visible role where your leadership directly influences clinical outcomes and client satisfaction.

• Lead the planning, execution, and delivery of Phase I–IV clinical trials, ensuring alignment with contractual scope, timelines, budgets, and regulatory requirements.
• Coordinate cross-functional teams including clinical operations, data management, biostatistics, regulatory, and vendors to ensure seamless project execution.
• Develop and maintain detailed project plans, including resource allocation, financial tracking, risk assessment, and mitigation strategies.
• Monitor project performance, track progress against milestones, and provide regular status updates to internal leadership and external sponsors.
• Manage client relationships, acting as the primary point of contact for project communication, issue resolution, and change order discussions.
• Ensure compliance with ICH guidelines, FDA, Health Canada, EMA, and other applicable regulatory standards throughout the project lifecycle.
• Identify and escalate project risks, resource gaps, or scope changes while ensuring timely corrective actions and resolution.

Requirements:

• Bachelor’s or Master’s degree in Life Sciences, Health Sciences, or a related field.
• 10+ years of experience in clinical research and development within a pharmaceutical, biotechnology, or CRO environment.
• At least 7 years of direct clinical project management experience across multiple phases of clinical trials.
• Strong knowledge of clinical trial processes including site selection, study start-up, monitoring, data management, regulatory submissions, and vendor management.
• Oncology clinical trial experience is required.
• Solid understanding of global regulatory frameworks including ICH, FDA, Health Canada, and EMA guidelines.
• Strong financial acumen with experience in budgeting, forecasting, and managing project profitability.
• Excellent leadership, communication, negotiation, and stakeholder management skills.
• Strong problem-solving abilities with the capacity to manage conflict and drive resolution in complex environments.
• Willingness to travel up to 20%, including internationally when required.

Benefits:

• Competitive salary range of $125,000 to $175,000 annually.
• Comprehensive medical, dental, and vision insurance coverage.
• Life, AD&D, short-term, and long-term disability insurance.
• 401(k) retirement savings plan.
• Generous paid time off and sick leave policy.
• Tuition reimbursement and fitness reimbursement programs.
• Employee assistance program (EAP) supporting well-being and mental health.
• Performance-based bonus opportunities.
• Remote-friendly work arrangement within the United States.