Senior Director of Target Discovery, Computational Biology and Human Genomic Sciences

Schrödinger's mission is to revolutionize drug discovery through the use of breakthrough computational methods. We are currently looking for outstanding individuals to join our drug discovery group and contribute to our rapidly expanding pipeline and portfolio of drug discovery collaborations.
Our drug discovery and early clinical development team includes a cross-functional group of scientists and drug developers with experience working on all common target classes and therapeutic areas. The group is supported by more than 100 software developers and engineers as well as a large-scale compute infrastructure to apply our proprietary physics-based drug design and optimization platform. Several programs we have worked on have achieved Development Candidates, including progression to clinical development and FDA approval. You can view our entire pipeline of wholly-owned programs and collaborations here.
We are looking for an accomplished, senior leader in genetics, bioinformatics and target identification to join our team of seasoned biologists, pharmacologists and computational biologists. The candidate will have a strong background in genetics and will lead a team focused on the translation of human data, including genomic and genetic information, into innovative new therapeutics by identifying and advancing drug targets that have strong evidence of a causal role in disease biology. The successful candidate will be responsible for providing strategic direction and lead development of genomic, genetic, and informatic approaches to new target discovery, patient stratification, and contribute to translational biomarker identification (based on genetic information) across the discovery portfolio.
Key Responsibilities:

• Lead a team of computational biologists and human geneticists. Set objectives for the team and develop, retain and hire key talent.
• Define a strategy and execution plan for the team to identify and progress high-quality targets based on large-scale human genetic and genomic datasets (e.g. data from the UK Biobank Life Sciences Consortium), as well as other public resources with the aim to initiate new drug discovery projects.
• In collaboration with disease area biologists, identify target-specific validation needs and work with experimental biologists to execute necessary target validation plan
• Contribute to the translational genomics efforts in support of the development of Schrödinger's clinical assets.
• Opportunity to join discovery project teams as biology or project lead or co-lead for projects that align with the candidates disease area biology expertise.

Essential Qualifications and Experience:

• Ph.D. in human genetics, bioinformatics or related field with 8+ years of relevant pharmaceutical or biotech experience.
• Extensive experience in identifying high value therapeutic targets in multiple disease areas, based on evaluation of human genetic and genomic data.
• Demonstrated experience in leading teams, and in developing and growing people.
• Expertise in immunology and oncology disease area biology.

Pay and perks:
Schrödinger understands it's people that make a company great. Because of this, we're prepared to offer a competitive salary, stock options, and a wide range of benefits that include healthcare (with dental and vision), a 401k, pre-tax commuter benefits, a flexible work schedule, and a parental leave program. We have regular catered meals in the office, a company culture that is relaxed but engaged, and over a month of paid vacation time. Our Office Management team also plans a myriad of fun company-wide events. New York is home to our largest office, but we have teams all over the world. Schrödinger is honored to have been included in Crain's New York Best Places to Work, BuiltIn's NYC Best Place to Work, and Newsweek's list of America's 100 Most Loved Workplaces.
Estimated base salary range: $250,000-$290,000 (NYC only). Actual compensation package is dependent on a number of factors, including, for example, experience, education, degrees held, market data, and business needs. If you have any questions regarding the compensation for this role, do not hesitate to reach out to a member of our Strategic Growth team.
Sound exciting? Apply today and join us!
As an equal opportunity employer, Schrödinger hires outstanding individuals into every position in the company. People who work with us have a high degree of engagement, a commitment to working effectively in teams, and a passion for the company's mission. We place the highest value on creating a safe environment where our employees can grow and contribute, and refuse to discriminate on the basis of race, color, religious belief, sex, age, disability, national origin, alienage or citizenship status, marital status, partnership status, caregiver status, sexual and reproductive health decisions, gender identity or expression, sexual orientation, or any other protected characteristic. To us, "diversity" isn't just a buzzword, but an important element of our core principles and key business practices. We believe that diverse companies innovate better and think more creatively than homogenous ones because they take into account a wide range of viewpoints. For us, greater diversity doesn't mean better headlines or public images - it means increased adaptability and profitability.