Senior Director, Protein Sciences

We are hiring a Senior Director, Protein Sciences with broad expertise in molecular biology, protein and antibody engineering. You will leverage your expertise to lead the engineering of synthetic protein constructs, including chimeric antigen receptors (CARs), for incorporation in cell therapy products. Reporting to the Chief Immunology and Cell Therapy Officer, you will be responsible for leading our Protein Sciences and Antibody group, which will oversee the generation and engineering of immune cells switch receptors, and other synthetic transgenes for incorporation on cell therapy product candidates. You will leverage your industry and academic experience in protein sciences to help lead the development of our therapeutic candidates. This role is based in Emeryville, California. 

• Build and lead our Protein Sciences team to help novel cell therapies for the treatment of cancer and auto-immune disorders
• Lead the implementation of antibody and protein engineering technologies to support engineering of our cell therapy product candidates
• Directly contribute to the selection and design of therapeutic candidates
• Motivate and lead a team of talented Scientists and Research Associates 
• Work collaboratively with key stakeholders in Cell Therapy and other company functions to support therapeutic candidate development
• Prepare accurate and timely data summaries and contribute to the writing of technical study reports, papers, patent applications, and regulatory filings
• Participate in regulatory interaction meetings and provide strategic communication to support IND filings.

• Ph.D. in STEM-related discipline and at least ten years of highly relevant biopharma industry experience
• Deep technical expertise in molecular biology, antibody, and protein engineering
• Experience with in vivo generation and screening of antibodies and in vitro antibody platforms including phage, yeast, and/or mammalian, display libraries
• Deep expertise with multiple antibody formats such as mAb, scFv, Fab, and single domain antibodies (VHHs)
• Experience in biochemical and biophysical characterization of biologics
• Experience engineering bi-specific antibodies, CARs, and membrane proteins
• Familiarity with laboratory automation and high throughput methods for protein production, purification, and characterization
• Familiarity with Bioinformatics tools for sequence and structural analysis to help drive binder selection
• Significant experience working with CROs, outsourcing, and managing external vendor relationships for antibody and protein generation.
• Extremely well organized and able to efficiently manage your time and workflows, including skillfully prioritizing both long-term projects and the day-to-day responsibilities of your team
• Direct supervisory experience leading teams of Scientists and Research Associates with a track record of recruiting, mentoring, and developing talent
• Outstanding communication, collaboration, and team leadership skills.

California Pay Transparency Disclosure:

This position is classified as an exempt salaried position under the Federal Labor Standards Act.  The anticipated base salary range for this position will be $245,000 -$265,000.  You will also be eligible to receive equity, bonuses, and a full range of medical, financial, and other benefits depending on the position offered. Please note that individual total compensation for this position will be determined at the Company’s sole discretion and may vary based on location, skill level, years and depth of relevant experience, and education. 

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