Senior Manager, Pipeline Strategy

Who We Are

Arcellx is a public, clinical-stage biotechnology company reimagining cell therapy by engineering innovative immunotherapies for patients with cancer and other incurable diseases. We believe that cell therapies are one of the forward pillars of medicine and our mission is to destroy cancer and advance humanity by developing cell therapies that are safer, more effective, and more broadly accessible.

Our team members are made up of talented innovators and dreamers working from our offices in Rockville, Maryland, and Redwood City, California. At Arcellx, we hire exceptional people and create a fun, diverse, supportive, and informal environment that allows everyone to do their best work.

What Matters to Us

Living our core values is essential to maintaining a work environment that is high-performing, inclusive, and collaborative. We look for candidates who demonstrate strong values alignment and bring different backgrounds, viewpoints, and abilities to the team.

Arcellx Core Values

• Character: Committed to always doing what’s right.
• Audacity: Willing to challenge convention and share candid feedback with others.
• Determination: Curious and self-motivated. Always looking to improve and learn.  
• Collaboration: "No job is too small" mentality. Humble and willing to help others.
• Originality: Will bring your unique perspective to the table and respect a diverse set of views and backgrounds.

How You’ll Make a Difference

In this role, you’ll use your expertise in crafting and delivering drug development strategies to manage pipeline projects from clinical candidate nomination through clinical proof of concept, including assessing ongoing project viability, management and oversight of key preclinical data updates, and readiness for IND preparation and filings.

This role has broad impact across the organization, working with cross-functional stakeholders, including senior management, to ensure alignment, timely decision making, and escalation of project challenges, ultimately maximizing the likelihood of clinical and commercial success.

The “Fine Print” – What You’ll Do

• Partner with our R&D team to develop and drive pipeline strategy.
• Manage timelines and budget across cross-functional workstreams, ensuring alignment of key deliverables, anticipating and mitigating risks, and driving accountability across the organization.
• Partner with functional leads to support CMC development and commercialization activities and ensure adequate clinical supply for the early and late-stage portfolio.
• Identify, develop, articulate, and present strategic options to make the best trade-off decisions within a project (e.g., technical product profile alterations, clinical product considerations) and across the portfolio as needed given changing market conditions or key early-stage data outputs.
• Present critical program updates for data read-outs or notable preclinical / clinical milestones to senior leadership.
• Ensure appropriate visibility to the organization on timeline, progress-to-date, upcoming key milestones, and identified risks.
• Escalate and resolve key issues with the senior management team.

Skills and Experience We Look For  

• Relevant industry experience in drug development. Manager to director-level candidates will be considered based on years of experience.
• Advanced degree preferred. 
• Strong grasp of the scientific methods used to develop immunotherapies for cancer.
• Broad understanding of the evolving clinical and global commercial landscape in oncology, autoimmune and inflammatory diseases, and cell therapy.
• Outstanding strategic planning and analytical skills with the ability to synthesize findings and articulate implications from multiple sources of information to formulate strong recommendations and uncover market opportunities.
• Demonstrated ability to unite complex cross-functional teams, build productive relationships, and influence senior leaders and key stakeholders.
• Ability to effectively project manage early-stage programs.

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