Senior Scientist - Assay Development

We seek an exceptionally collaborative Senior Scientist with experience in bioassay development to be part of a truly integrated R&D team. The successful candidate would have a track record with a range of cell biology techniques employed to uncover novel biology and develop assays for therapeutic programs. Familiarity with genetic screening methodologies would be an advantage.  Since we are an actively growing start-up, we also seek creative thinkers, agile learners and candidates with an unwavering willingness to do what is necessary to help build the company and mature a human-genetics-backed therapeutic pipeline. Our current disease areas of interest include kidney disease, fibrosis, inflammation, and neurodegenerative disorders.

Responsibilities

• Design and implement robust functional assays to support the identification and characterization of novel drugs.
• Develop the appropriate bioassays to link disease-causing genetic variants to their relevant genes, cell types, molecular pathways and disease phenotypes.
• Responsible for establishing and managing CROs for assay development.
• Help in the identification and assessment of new technologies.
• Contribute to deep dives into relevant disease areas and GWAS-identified targets to support a competitive R&D pipeline.
• Work together with medical biologists and internal computational geneticists to establish assays and advance genetic findings.  
• Effectively communicate scientific results to internal and external audiences.
• Contribute to scientific publications.

Qualifications

• BA or Masters and 10+ years of experience or PhD and 5+ years of experience in cell biology, immunology, or related field. Industry experience preferred.
• Experience with various assay platforms and the ability to develop robust cell-based assays including flow cytometry, multiplexing assays and cell imaging techniques, to support drug discovery. Mouse assay development is a plus.
• Ability to work across cross-functional teams and support more than one project.
• Proven record in establishing connections with CROs and collaborators.
• Familiarity with the process by which therapeutics and/or diagnostics are discovered and developed.
• Strong people skills and an ability & willingness to work on a multidisciplinary R&D team.
• Independent, creative, detail-oriented, and a critical thinker. 
• Kidney disease, fibrosis or genetics expertise is an advantage.   
• Compelled by the company’s mission of great science, a strong ethical stance, and benefit sharing.

Perks

• Opportunity to be part of a startup entering a rapid growth phase grounded in ethics.
• Competitive salary and equity packages as well as a 401(k) plan that includes an automatic 3% employer contribution.
• Comprehensive benefits including medical, dental and vision with 100% of monthly employee premiums paid for by the company.
• Flexible paid time off to help employees obtain a healthy work-life balance.
• Company paid professional development opportunities to encourage career progression.
• Orca Card provided by the company for work related transportation.
• Centrally located Eastlake, Seattle location in a new Alexandria building with modern facilities, including a gym.