Senior Scientist, In Vitro Pharmacology

Key Responsibilities and Activities

• Design, develop, and execute cell-based bioassays to evaluate performance of investigative drugs (biologics)
• Stay updated with cutting edge discoveries and trends and contribute to the company’s R&D strategy to generate and test actionable development plans
• Identify emerging methods, tools, and biology approaches, and implement them when applicable
• Function as a key team member, and simultaneously train and supervise associates on the R&D team
• Collaborate closely with other scientists and research associates on the R&D team
• Contribute to work with external parties, including academic collaborators and CROs to create comprehensive capabilities for MoA, target validation and potency studies
• Write clear and concise research reports and ensure study documentation and update protocols to ELN
• Participate and contribute to internal discussions and meetings
• Present results to the project leadership team and management in an organized and timely manner

Required Education, Experience, Skills and Competencies

• Ph.D. in Cellular Biology, Immunology, or a relevant discipline
• At least 2 years of industry research experience
• Extensive experience working with different types of in vitro systems such as immune cells, epithelial cells, fibroblasts, endothelial cells, and other cell lines
• Strong background with cell-based assays to interrogate immune pathway activation, immune suppression, cytotoxicity, antibody mediated cell killing
• Broad skillset for target validation, potency evaluation and MoA interrogations is highly desired, including the use of tissue culture approach with multiple readouts, flow cytometry, ex-vivo studies, use of gene knockdown tools, conventional immunoassays, phosphorylation analysis and conventional pulldown assays.
• Hands on ability to execute wet lab experiments, data processing, and ability to effectively communicate key scientific findings across the organization
• Ability to establish and maintain cooperative working relationships with co-workers and other stakeholders
• Ability to adjust to workload changes and prioritize competing demands
• Ability to balance the big picture and fine technical details
• Outstanding organizational, critical thinking, and problem-solving skills
• Excellent written and verbal communication skills