Senior Scientist MedChem (Synthesis)

The heart of insitro’s strategy is the combination of novel, cutting edge methods in machine learning, biology at scale and drug discovery capabilities that address key bottlenecks in the drug development pipeline. To accomplish that, we are putting together an incredible team of highly talented drug discovery scientists who want to make a difference by bringing meaningful and accessible medicines to patients with significant unmet needs. In this key role, you will help build the medicinal chemistry and drug discovery capabilities.

Key Responsibilities:

• Guide synthetic chemistry efforts (intermediate synthesis, route scouting/optimization, scale ups) across multiple projects
• Work cross-functionally to drive drug discovery projects through different stage gates towards clinical development candidates
• Lead synthetic chemistry CRO efforts
• Explore new approaches to utilize machine learning in drug discovery.

You will be joining a growing biotech startup that has long-term stability due to significant funding, but yet is very much in formation. A lot can change in this early and exciting phase, providing many opportunities for significant impact. You will work closely with a very talented team, learn a broad range of skills, and help shape insitro’s culture, strategic direction, and outcomes. Join us, and help make a difference to patients!

- PhD in synthetic organic chemistry or medicinal chemistry with 5+ years of industry experience in drug discovery
- Demonstrated track record of advancing projects through different stages of drug discovery
- High level of creativity and productivity towards solving synthetic problem 
- Strong ability to influence and drive creative chemistry efforts towards project milestones
- Proven leadership capabilities in cross-functional teams as synthetic chemistry leader
- Experience leading process chemistry workflows
- Track record of innovation and impact on projects through peer-reviewed publication and/or patent applications
- Working knowledge of drug discovery principles and techniques beyond medicinal chemistry 
- Experience managing scientific collaboration and CRO resources
- Excellent written and verbal communication skills across multi-functional teams
- Intellectual curiosity to push the boundaries of drug discovery