Senior Scientist - Pharmacokinetic/Pharmacodynamic Modeler

Are you passionate about developing biological models and simulating the pharmacokinetic behavior of drugs and chemicals? Are you interested in working with a multidisciplinary team of senior staff including mathematicians, biologists, and engineers? Would you like to work for a company that values dedication in the workplace, promotes learning and professional development, and appreciates the importance of work-life balance? If so, we would like to talk to you about your research interests!

Applied Research Associates, Inc. (ARA) is seeking a Senior Scientist to join the Computational Modeling and Respiratory Dosimetry (CMRD) Group in the Algorithms, Modeling, and Assessments Division. In addition to a background in biology and mathematics, the successful candidate should have a keen interest in exposure and respiratory dosimetry of inhaled materials and a working knowledge of one or more programming languages.

In this role, you will work with a multidisciplinary team to design, develop, and implement biological models to simulate the deposition, absorption, distribution, metabolism, and excretion of inhaled drugs and chemicals in the body. The types of research problems that will be addressed include, for example, inhalation of chemical and biological agents, drugs delivered intranasally and to the lungs, and exposure to tobacco product constituents such as nicotine. The ideal candidate will have a degree in applied mathematics, quantitative biology, or toxicology and a solid background in human physiology, inhalation toxicology, and risk assessment. The candidate should have demonstrated experience in the development and application of physiologically-based pharmacokinetic/pharmacodynamic (PBPK/PD) or other biologically-based models, in-vitro to in-vivo extrapolation, and the use of computational toxicology techniques for extrapolation of in vitro and in vivo data for human health risk assessments. The candidate should be motivated by the desire to solve complex problems and demonstrate a keen interest in business development related to pharmacokinetic modeling. You will join an established team that is focused on developing modeling frameworks for drug delivery, inhalation toxicology, and improved risk assessment protocols for human exposure.

Senior Scientist - Pharmacokinetic/Pharmacodynamic Modeler Position Requirements:

• Must be able to obtain a U.S. government security clearance which includes U.S. citizenship
• Ph.D. degree in Engineering, Applied Mathematics, Biomathematics, Toxicology, or a related discipline along with a minimum of three years of experience developing PBPK/PD models for toxicological or pharmaceutical applications
• Strong quantitative background in biological modeling
• Experience programming in Matlab, R, and Python
• Demonstrated research and writing skills as evidenced by technical writing
• Ability to work collaboratively with a research team and work independently with little supervision
• A keen interest in business development centered around pharmacokinetic modeling

Senior Scientist - Pharmacokinetic/Pharmacodynamic Modeler Position Preferences:

• Experience in computational toxicology and risk assessment methods
• Demonstrated experience in business development, marketing, and proposal/grant writing
• Programming experience in C++, Python, or Java
• Strong publication record
• Active DoD security clearance is desirable

Anticipated salary range: $130,000 - $160,000. Offer may vary depending on experience and skill set.

About Us:

Applied Research Associates, Inc. (aka ARA) is an employee-owned international research and engineering company known for providing technically superior solutions to complex and challenging problems in the physical sciences. We were founded in Albuquerque, NM in 1979 as the disco era was, thankfully, closing out and the personal computer era was beginning. We employ over 1,500 professionals and continue to grow. ARA offices throughout the U.S. and Canada provide a broad range of technical expertise in defense, civil, and health technologies, computer software, and simulation, systems analysis, environmental technologies, and testing and measurement.

ARA also prides ourselves on having a challenging culture where innovation & experimentation are the norm. At ARA, employees are our greatest assets, so we give our employees the tools, training, and opportunities to take active roles as owners. The motto, "Engineering and Science for Fun and Profit" sums up the ARA experience. The company realizes employee ownership spawns greater creativity and initiative along with higher performance and customer satisfaction levels. We are also very proud of our Women's Initiative Network (WIN) whose purpose is to motivate, support, and encourage professional career development for women to maximize career and professional accomplishments.

To find out more about Algorithms, Modeling & Assessments Division visit our website at: https://www.ara.com/raleigh/

Equal Opportunity Employer/Protected Veterans/Individuals with Disabilities

The contractor will not discharge or in any other manner discriminate against employees or applicants because they have inquired about, discussed, or disclosed their own pay or the pay of another employee or applicant. However, employees who have access to the compensation information of other employees or applicants as a part of their essential job functions cannot disclose the pay of other employees or applicants to individuals who do not otherwise have access to compensation information, unless the disclosure is (a) in response to a formal complaint or charge, (b) in furtherance of an investigation, proceeding, hearing, or action, including an investigation conducted by the employer, or (c) consistent with the contractor's legal duty to furnish information. 41 CFR 60-1.35(c)