Senior Vice President, Clinical Development Oncology

This position is posted by Jobgether on behalf of a partner company. We are currently looking for a Senior Vice President, Clinical Development Oncology in the United States.

This role leads the clinical advancement of oncology programs, focusing on strategic planning, operational execution, and regulatory oversight across early- to late-stage trials. The Senior Vice President will design and implement clinical development strategies, guide cross-functional teams, and ensure high-quality execution in alignment with global regulatory standards. This leader will build and mentor a high-performing clinical team, drive trial design and data interpretation, and cultivate relationships with investigators and key opinion leaders. Operating in a fast-paced, growth-oriented environment, the role requires a combination of scientific expertise, strategic vision, and hands-on leadership to advance programs from concept to pivotal inflection points while delivering meaningful impact for patients.

• Lead the clinical development strategy for oncology programs, including cholangiocarcinoma and hepatocellular carcinoma.
• Design, oversee, and execute clinical protocols from Phase 1 through pivotal studies, ensuring scientific rigor and regulatory compliance.
• Manage and mentor a cross-functional clinical team, including clinical operations, pharmacology, biostatistics, and other subject matter experts.
• Interface with global regulatory authorities and support submissions, study reports, and approvals.
• Build relationships with investigators, select trial sites, and monitor study execution for quality and compliance.
• Provide clinical insights for regulatory documents, study design, statistical plans, and safety monitoring.
• Act as primary medical monitor for assigned trials, ensuring patient safety and data integrity.

Requirements:

• MD preferred; advanced scientific degree (PhD, PharmD) considered with relevant experience.
• 10–15+ years of clinical development experience in biotech or pharmaceutical settings, with a strong oncology focus.
• Direct experience in liver cancers (HCC, cholangiocarcinoma) strongly preferred.
• Familiarity with early- and late-phase clinical trial design, global regulatory requirements, and GCP/ICH/FDA standards.
• Proven ability to build, lead, and mentor clinical teams and manage cross-functional collaborations.
• Demonstrated success in regulatory submissions and engagement with key opinion leaders (KOLs).
• Strong analytical skills with the ability to interpret complex data and communicate results effectively.
• Thrive in a fast-paced, dynamic, and remote work environment with a proactive, problem-solving mindset.

Benefits:

• Competitive annual base salary range: $300,000 – $450,000.
• Discretionary bonus opportunities.
• Comprehensive benefits package including medical, dental, vision, and retirement plan options.
• Paid time off and flexible work arrangements.
• Leadership role with strategic impact on oncology program development.
• Opportunity to work in a high-growth, patient-focused biotech environment.