Senior/Principal Research Associate (Neuroscience)

About Voyager

 Voyager Therapeutics (Nasdaq: VYGR) is a biotechnology company dedicated to breaking through barriers in gene therapy and neurology. The potential of both disciplines has been constrained by delivery challenges; Voyager is leveraging innovative expertise in capsid discovery and deep neuropharmacology capabilities to address these constraints. Voyager’s TRACER AAV capsid discovery platform has generated novel capsids with high target delivery and blood-brain barrier penetration at low doses, potentially addressing the narrow therapeutic window associated with conventional gene therapy delivery vectors. This platform is fueling alliances with Pfizer Inc., Novartis and Neurocrine Biosciences as well as multiple programs in Voyager’s own pipeline. Voyager’s pipeline includes preclinical programs in Parkinson’s disease, Alzheimer’s disease, and amyotrophic lateral sclerosis (ALS), each with validated targets and biomarkers to enable a path to rapid potential proof-of-biology. For more information, visit www.voyagertherapeutics.com

Job Summary

We are currently seeking an experienced and highly motivated Senior/Principal research associate who shares our passion for the promise of gene therapy. The successful candidate will work with our multidisciplinary team in Cambridge, Massachusetts. This is an ideal position for an individual with a strong background in preclinical rodent in vivo experiments, who thrives in a team-oriented, fast-paced, and cross-disciplinary start-up biotech environment.

The individual will design and execute hands-on in-house rodent studies to support platform and discovery research. The successful candidate will interact with cross-functional Neuroscience Research program teams to execute in vivo pharmacology and efficacy studies using gene therapy approaches. The candidate will analyze data and communicate study progress and data through presentations and reports.

Key Responsibilities

• · The individual will be responsible for experimental design, execution and data analysis for research studies supporting platform and discovery research
• · Design and hands-on execute rodent in vivo experiments including experiments in animal models of neurodegenerative disease
• · Performing test article dosing via various administration routes (e.g. IV, brain stereotactic infusions), brain and tissue collection, and downstream analysis (e.g. RT-qPCR, bDNA, western blot and ELISA).
• · Performing data analyses and delivering data presentation to teams
• · Ensuring maintenance of industry-quality records and proper documentation
• · Monitor health, perform behavioral assessments and tissue/blood collection

Qualifications

• ·A Master’s degree with a minimum of 8 years of experience or a Bachelor’s Degree with a minimum of 10 years of experience is required
• · A minimum of 8 years of hands-on experience with performing test article administration in rodent (mouse and rat) is required
• · Experience in neuroscience is required
• · Technical proficiency with a wide variety of rodent in vivo pharmacology skills (IV, IP, stereotactic delivery)
• · Conducting ex vivo tissue analysis (i.e. Digital ELISA, RT-qPCR, etc)
• · Outstanding problem-solving skills and ability to multi-task
• · Self-motivated, able to work independently, highly organized with strong attention to detail

Voyager Therapeutics requires all U.S. new hires to be fully vaccinated for COVID-19 prior to the first date of employment.  Voyager Therapeutics will consider reasonable accommodations as required by federal, state, and local laws.