Sr Manager Software Engineering

Passionate about precision medicine and advancing the healthcare industry?

Recent advancements in underlying technology have finally made it possible for AI to impact clinical care in a meaningful way. Tempus' proprietary platform connects an entire ecosystem of real-world evidence to deliver real-time actionable insights to physicians providing critical information about the right treatments for the right patients at the right time.

In this leadership capacity you will manage a small team of engineers leveraging cutting-edge AI-assisted development tools to accelerate delivery.

• Team Leadership & Mentorship: Lead and manage a small agile team of software engineers. Conduct code reviews provide technical guidance and foster a culture of excellence in data quality and engineering best practices.

• DBT Testing & Quality Gates: Architect and implement a comprehensive testing suite within DBT. Design and enforce data quality gates in the CI/CD and ETL  pipeline to ensure that only high-integrity data reaches production environments.

• Deep Data Analysis & Profiling: Perform exhaustive data profiling and deep-dive analyses using SQL and Python to evaluate completeness identify hidden patterns and resolve structural inconsistencies.

• Product Strategy & Planning: Collaborate directly with Product Managers and other Team Leads to develop and prioritize the product backlog. You will be responsible for identifying work estimates and refining complex requirements into actionable technical tasks.

• Modern Data Stack & Observability: Architect and implement robust observability frameworks using BigQuery DBT Elementary and Grafana to create real-time monitors alerts and dashboards that track the health and lineage of our data ecosystem.

• AI-Driven Development: Champion the use of AI productivity tools—such as Cursor Claude and GitHub Copilot—to streamline development automate testing and refactor legacy data pipelines efficiently.

• Statistical Insights & KPIs: Define and report on key Data Quality KPIs (e.g. freshness volume and schema changes) using correlation and trend analysis to provide platform-wide transparency.

• Advanced Data Modeling: Manage an enterprise data model integrating multiple domains (Clinical NGS Radiology) across relational and NoSQL technologies.

• Technical Proficiency: You are an expert in the modern data engineering stack specifically DBT SQL and Python.

• Leadership Experience: You have a proven track record of leading or mentoring a small team of engineers in a fast-paced environment.

• Observability & AI Savvy: You have hands-on experience with observability tools (e.g. Elementary Grafana) and are proficient in leveraging AI coding assistants (Cursor Claude Copilot) to enhance team velocity.

• Domain Expertise: You have a strong background in healthcare and next-generation sequencing (NGS) data.

• Analytical Powerhouse: You use data profiling and correlation analysis to solve complex data integrity problems.

• Communication: Ability to translate technical data quality gaps into actionable insights for both internal developers and external stakeholders.

Chicago: $150000 - $210000

NY/SF: $175000 - $225000

The expected salary range above is applicable if the role is performed from Illinois and may vary for other locations (California Colorado New York). Actual salary may vary based on qualifications and experience. Tempus offers a full range of benefits which may include incentive compensation restricted stock units medical and other benefits depending on the position.

We are an equal opportunity employer. We do not discriminate on the basis of race religion color national origin gender sexual orientation age marital status veteran status or disability status. 

What We Do

We bring together one of the world’s largest libraries of multimodal clinical and molecular data with a robust suite of AI tools to help physicians personalize care in real time connect patients with therapies and clinical trials and enable partners to accelerate discovery and development of new treatments. With ~8 million de-identified research records and 350+ petabytes of data Tempus partners with more than half of U.S. oncologists and the majority of the top 20 global pharma companies. Our teams are pioneering work across oncology neurology psychiatry cardiology and beyond—transforming how care is delivered and therapies are developed. At Tempus every role contributes to our mission: to help each patient benefit from the experiences of those who came before. For more information visit tempus.com.

Why Work With Us

We’re looking for people who can change the world. People who question the status quo and refuse to shy away from tough problems. For builders who are never done building and the learners who are never done learning. Passionate individuals with undying curiosity who want to take on one of the greatest challenges humanity has ever faced—head on.

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