Staff Software Engineer – Data Team (Menlo Park, CA) #4433

· Remote

Location

Remote

Type

Full Time

Job Description

Staff Software Engineer – Data Team (Menlo Park CA) #4433

Reposted 15 Hours Ago
2 Locations
Hybrid
163K-216K Annually
Senior level
Artificial Intelligence • Big Data • Healthtech • Machine Learning • Software • Biotech
GRAIL is a healthcare company whose mission is to detect cancer early when it can be cured.
The Role
Collaborate to design deploy and automate secure data infrastructure. Ensure data quality and compliance while mentoring team members. Drive innovative data solutions.
Summary Generated by Built In
Our mission is to detect cancer early when it can be cured. We are working to change the trajectory of cancer mortality and bring stakeholders together to adopt innovative safe and effective technologies that can transform cancer care.

We are a healthcare company pioneering new technologies to advance early cancer detection. We have built a multi-disciplinary organization of scientists engineers and physicians and we are using the power of next-generation sequencing (NGS) population-scale clinical studies and state-of-the-art computer science and data science to overcome one of medicine’s greatest challenges.

GRAIL is headquartered in the bay area of California with locations in Washington D.C. North Carolina and the United Kingdom. It is supported by leading global investors and pharmaceutical technology and healthcare companies.

For more information please visit grail.com

GRAIL is seeking a Staff Software Engineer for the Data Team.  This team designs builds and operates the software systems that manage GRAIL’s end-to-end data lifecycle from sample ingestion through downstream analysis while meeting rigorous clinical regulatory and privacy standards. Our work directly supports clinical research operations and decision-making in the fight against cancer.

In this role you will take technical ownership of systems that produce trusted analysis-ready datasets for use across GRAIL’s research and clinical programs. This is a software engineering role focused on building complex production-grade systems that work with data in dynamic regulated environments as opposed to assembling off-the-shelf ETL tools or writing SQL heavy pipelines.This position offers significant autonomy and scope for impact. You’ll collaborate closely with research clinical lab operations and scientific teams and lead efforts to improve how we structure validate and deliver critical scientific and clinical data.

This is a hybrid role based in either Menlo Park CA (moving to Sunnyvale CA in Fall 2026) or Durham NC. Our current hybrid policy requires on-site presence at least 60% of the time including key in-person collaboration days.

Responsibilities

  • Design and implement software systems that turn raw clinical lab and operational data into reliable analysis-ready datasets
  • Partner with scientists clinicians lab operations and data teams to understand data generation transformation and usage needs
  • Develop services libraries data models and workflow components that enforce data integrity access control and compliance by design
  • Navigate complex data requirements such as schema evolution blinding consent and privacy compliance
  • Collaborate on cross-functional initiatives involving data quality testing strategy monitoring and operational excellence
  • Lead software engineering efforts for long-lived systems that must evolve alongside active clinical and research programs
  • Mentor engineers and collaborate with scientists to ensure software decisions support both technical and scientific outcomes
  • [Contribute to documentation onboarding materials and processes that support cross-functional adoption and data literacy across teams]
  • [Participate in incident response or investigation processes related to data quality or availability issues in production systems]

  • These responsibilities summarize the role’s primary responsibilities and are not an exhaustive list. They may change at the company’s discretion.

Required Qualifications

  • 7+ years of experience building production-grade software systems
  • Strong software engineering fundamentals including system design data modeling API design and writing well-tested production code.
  • Experience building and operating data-intensive software systems not just declarative pipelines or SQL-only workflows
  • Proficiency in Go or Python (or similar general-purpose language)
  • Experience with data modeling validation and transforming real-world data into usable formats
  • BS in Computer Science Engineering or Bioinformatics or a related field or equivalent practical experience

Preferred Qualifications

  • 2+ years experience working in regulated or clinical data environments (e.g. HIPAA CLIA GCP FDA compliance)
  • Direct experience working with or supporting scientific teams (e.g. bioinformatics wet lab clinical research)
  • Experience designing systems that manage laboratory or bioinformatics data (e.g. LIMS sequencing pipelines assay metadata)
  • Familiarity with GxP practices and regulatory reporting requirements in clinical studies is a plus
  • Prior experience working in biotech diagnostics or life sciences companies
  • Experience supporting sample tracking structured scientific data pipelines or cross-functional data lifecycle management
  • Experience designing systems with data sequestration permissioning or privacy controls
  • Experience writing or contributing to software libraries shared tooling or reusable components used by other teams
  • Advanced degree (MS or PhD) in computer science engineering bioinformatics or a related discipline

Expected full time annual base pay scale for the bay area is $163K-$216K. Actual base pay will consider skills experience and location.

This role may be eligible for other forms of compensation including an annual bonus and/or incentives subject to the terms of the applicable plans and Company discretion. This range reflects a good-faith estimate of the range that the Company reasonably expects to pay for the position upon hire; the actual compensation offered may vary depending on factors such as the candidate’s qualifications. Employees in this role are also eligible for GRAIL’s comprehensive and competitive benefits package offered in accordance with our applicable plans and policies. This package currently includes flexible time-off or vacation; a 401(k) retirement plan with employer match; medical dental and vision coverage; and carefully selected mindfulness programs.

GRAIL is an equal employment opportunity employer and we are committed to building a workplace where every individual can thrive contribute and grow. All qualified applicants will receive consideration for employment without regard to race color religion national origin sex gender gender identity sexual orientation age disability status as a protected veteran or any other class or characteristic protected by applicable federal state and local laws. Additionally GRAIL will consider for employment qualified applicants with arrest and conviction records in a manner consistent with applicable law and provide reasonable accommodations to qualified individuals with disabilities. Please contact us at [email protected] if you require an accommodation to apply for an open position.

GRAIL maintains a drug-free workplace. We welcome job-seekers from all backgrounds to join us!

Top Skills

Apache Airflow
Aws Glue
Dbt
Kubernetes
Python
Spark
SQL
Terraform

What the Team is Saying

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Tristan Matthews
David Jenions
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The Company
HQ: Menlo Park CA
918 Employees
Year Founded: 2016

What We Do

GRAIL is a healthcare company whose mission is to detect cancer early when it can be cured. GRAIL is using the power of high-intensity sequencing population-scale clinical studies and state-of-the-art computer science and data science to enhance the scientific understanding of cancer biology and to develop and commercialize pioneering products.

Why Work With Us

Everything we do is guided by our mission to detect cancer early when it can be cured. It’s the reason we’re here and it’s no small task. The right people make all the difference. That’s why we’re looking for those who strive to share their knowledge contribute their skills inspire each other and commit to something bigger than themselves.

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GRAIL Offices

Hybrid Workspace

Employees engage in a combination of remote and on-site work.

GRAIL has a variety of work types depending on the roles. Some are onsite like a lab role others are hybrid and still others are remote. Hybrid is typically Tuesday and Thursday but leaders may be flexible depending on the role.

Typical time on-site: 2 days a week
Company Office Image
HQMenlo Park CA
Company Office Image
London GB
Company Office Image
Raleigh NC
Company Office Image
Washington DC
Learn more

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Date Posted

03/26/2026

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