USP Labs, SME

Work Schedule
Other

Environmental Conditions
Laboratory Setting, Some degree of PPE (Personal Protective Equipment) required (safety glasses, gowning, gloves, lab coat, ear plugs etc.), Will work with hazardous/toxic materials

Job Description

Thermo Fisher Scientific Inc. is a global leader in serving science with annual sales of more than $40 billion. Our mission is to help our customers make the world healthier, cleaner and safer. We support our customers advance life science research, solve complex analytical challenges, increase efficiency in their laboratories, improve patient health through diagnostics, or develop and manufacture life-enhancing therapies.

We are more than 100,000 colleagues to offer an unmatched combination of innovative technologies, convenient purchasing processes and pharmaceutical services through our industry-leading brands, including Thermo Scientific, Applied Biosystems, Invitrogen, Fisher Scientific, Unity Lab Services, Patheon and PPD.

The brand new multi-purpose manufacturing and development site in Lengnau is designed for large scale biologics manufacturing and has a vast expansion potential. Our Lengnau site offers highly flexible biomanufacturing technologies from process development to large-scale production to successfully meet the needs of our customers.

USP Labs, SME, Process Development (m/f/d)

Location: Lengnau, BE, Switzerland

In this position, you will lead projects related to upstream process development for our clients. You will provide complex analysis as a USP subject matter expert with independent judgment. Your role involves developing scalable processes with a focus on process improvement, facility fit to manufacturing, improved product yield, and reduced costs in a biologics environment.

You will be a key player in our day-to-day lab activities, with responsibility for specific equipment, lab areas, lab consumables, and chemicals. Additionally, you will participate in the strategic development of our process technology platform and collaborate with other areas of internal development and/or manufacturing operations. Your responsibilities include making detailed observations, analyzing, and resolving issues, documenting, and communicating test results.

Your Responsibilities:

• Lead and execute upstream process development studies to support the production of recombinant proteins (including mAbs). Perform media optimization, seed train development, bioreactor process development, and cell culture clarification.

• Represent USP Labs in cross-functional teams. Plan project scope, timing and resource requirements to meet the defined deliverables.

• Supports technology transfer as sending and/or receiving unit. Works with Process Development and Manufacturing groups to trouble-shoot process challenges.

• Author, review and approve reports, study plans, protocols, SOPs, and work instructions. Document execution and results according to good documentation practices.

• Act as equipment responsible, ensuring maintenance and the preparation of standard operating procedures for equipment and/or methods. Take ownership for housekeeping, coordination and safety for specific lab areas.

• Willingness to work weekends on a rotational basis. Infrequently, international travel (≤10%) and participation at international calls throughout various time zones may be requested.

Your profile:

• Degree (M.Sc. or PhD.) in Life Sciences (Biology, Chemistry, etc.), Dipl. Ing. or equivalent.

• 5+ years of industry experience related to Biologics manufacturing, upstream process development and process engineering for candidates with a Master's degree. Prior exposure to GxP is an advantage.

• Upstream bioprocessing experience with mammalian cell cultures.

• Demonstrated experience working with bioreactors (bench scale, pilot scale, AMBR250). Experience with perfusion processes and Design of Experiments is an advantage.

• Excellent communication, self-organization, can-do attitude and problem-solving skills, coupled with a customer-centric focus

• Proficient with Microsoft Office applications (Word, Excel, PowerPoint)

• Reliable teammate that excels in a multicultural, international environment.

Our offer:

You can expect a varied job in a dynamic and international environment. A culture in which integrity, intensity, involvement and innovation are lived. A well-founded induction and task-specific training are a matter of course for us. You will define your future in our company - make your contribution to our joint success!

Have we aroused your interest?

Then we look forward to receiving your meaningful and complete application documents (max. 2MB), stating the relevant job ID, your salary expectations and your period of notice. Apply online today via our career site https://jobs.thermofisher.com.

Each of our 100,000 outstanding individuals at Thermo Fisher Scientific has a very personal story. Join us and contribute to our unique mission.

Thermo Fisher Scientific is committed to equal opportunity as an employer and does not discriminate on the basis of ethnicity, color, religion, sex, sexual orientation, gender identity, national origin, disability or legally protected status.