Variant Scientist, Therapies Lead

Passionate about precision medicine and advancing the healthcare industry?

Recent advancements in underlying technology have finally made it possible for AI to impact clinical care in a meaningful way. Tempus' proprietary platform connects an entire ecosystem of real-world evidence to deliver real-time, actionable insights to physicians, providing critical information about the right treatments for the right patients, at the right time.

We are looking for a Variant Scientist Therapies Lead who will be responsible for ensuring updated and appropriate therapies are applied to clinical reports. They will work with other members of team leadership, medical science, Pathologists, and the Technology org to ensure smooth implementation of Therapies reporting updates into clinical production. Additionally, the Therapies Lead will interpret patients’ genetic data and prepare clinical reports as a Variant Scientist. 

Members of our Variant Science team work a variety of schedules (primarily Sunday-Thursday or Tuesday-Saturday) in order to best serve our patients. A shift differential is applied for team members who are regularly scheduled to work a weekend day.

 Responsibilities Include:

• Proficiency as a Variant Scientist or higher level with an understanding of Tempus processes, interconnected products, and policies.
• Help design, build, and maintain Clinical Science Therapies reporting workflows that are scalable, scientifically correct, and clinically responsible. 
• Assist in planning and executing on yearly initiatives and quarterly goals.
• Identify areas of improvement and generate project plans to address those areas.
• Act as key stakeholder for Therapies updates, effectively communicate changes in SOP with other stakeholders (i.e., Medical Science, Pathology, and Product teams)
• Monitor and respond to therapy-related queries from Variant Scientists and external teams to support clinical reporting. Drive the Therapies Squad to support clinical reporting.
• Assist the trainer to train the Clinical Science Oncology team in Therapies, update checklists and SOPs as needed for process changes
• Clinical case review:
• Accurately classify somatic and germline variants for solid tumor and liquid biopsy NGS panels
• Utilize a variety of in-house software tools to analyze clinical molecular data
• Read and interpret scientific literature and curate relevant findings in a clear, concise, and precise manner
• Summarize somatic and inherited genetic test results to generate high quality clinical reports
• Perform critical quality control functions for molecular reports that comply with quality management programs and standard operating procedures

Preferred Qualifications:

• MS or PhD degree in Cancer Genetics, Human Genetics, or Biological Sciences
• Prior experience in a diagnostic laboratory, clinical report writing, and familiarity with human mutation databases, genome browsers, and HGVS nomenclature is preferred. Oncology experience strongly preferred
• Must have utmost attention to detail, excellent communication, and writing skills
• Ability to accurately follow formal documentation and protocols
• Ability to work in both an individual and group setting. Must be flexible and able to adjust priorities according to workload or management needs