Tech Jobs in Cleveland, Ohio

31,080 open positions · Updated daily

Cleveland hosts over 4,000 tech openings, blending startups with established firms that prioritize software, data, and hardware talent. A strong university presence, manufacturing talent pool, and city‑wide innovation incentives create a vibrant hiring climate.

Key employers include Cleveland Clinic’s data science teams, Rockwell Automation’s embedded engineering, Progress Software’s cloud platform, GoDaddy’s digital marketing tech, and Itron’s smart‑grid solutions. Fintech firms such as KeyBank’s digital banking division and health‑tech startups in University Circle add to the diversity.

The city’s cost of living is roughly 25% below the national average: median rent near $1,300, single‑family homes around $210,000. Salary transparency helps you align affordable living with competitive pay, ensuring a stable lifestyle while advancing your career.

Sr. Analyst, Quality Control

Company: Abeona Therapeutics

Location: Cleveland, OH

Posted Jan 30, 2025

The Quality Control Senior Analyst I position involves driving routine laboratory activities in support of Good Manufacturing Practices (GMP) testing. The role includes conducting training, serving as a backup analyst for Environmental Monitoring, authoring and revising analytical methods, reviewing documentation, participating in validation, driving process improvements, and maintaining laboratory compliance. The ideal candidate should have a BS in biochemistry, biology, microbiology, molecular biology, or a related field with 5-7 years of relevant experience in the pharmaceutical or biotech industry. Good mathematical and organizational skills, as well as the ability to interact constructively with coworkers, are required.

Quality Control, System Administrator

Company: Abeona Therapeutics

Location: Cleveland, OH

Posted Jan 30, 2025

The Quality Control System Administrator role involves ensuring the implementation and rollout of third-party business applications, such as Laboratory Information Management Systems (LIMS). The position requires technical expertise in analyzing, designing, developing, testing, implementing, supporting, and documenting complex business applications. The administrator will be responsible for maintaining and managing installs, upgrades, patches, and troubleshooting of third-party packaged business applications. They will also handle support tickets, collaborate with software developers, and perform other duties as assigned. The ideal candidate should have a BS in Biochemistry, Biology, Microbiology, Molecular Biology, Computer Science, or a relevant discipline, with 2-4 years of related LIMS experience. Familiarity with IT systems in a Laboratory environment and proficiency in the Windows environment are required. Some weekend work or late nights may be required periodically.

Quality Control Analyst I (QC Analytical)

Company: Abeona Therapeutics

Location: Cleveland, OH

Posted Jan 30, 2025

The Quality Control Analyst I position involves performing routine laboratory activities in support of Good Manufacturing Practices (GMP) testing for Quality Control (QC). The role includes tasks such as qPCR, immunostaining, protein characterization, and product-specific analytical test methods. The analyst will interact with employees both internally and externally to Quality Control. Essential duties include training on SOPs and methods, performing in-process and finished drug product analysis, maintaining organized laboratory records, and contributing to improving QC systems and procedures. The ideal candidate should have a BS in a relevant discipline with 1-3 years of experience, preferably in the pharmaceutical or biotech industry within a GMP or GLP environment. Experience in cell culture, qPCR, and protein analysis is preferred. Good mathematical and organizational skills, along with the ability to interact constructively with coworkers, are required. Some weekend work or late nights may be necessary periodically.

Frequently Asked Questions

What types of tech jobs are available in Cleveland, Ohio?
Software engineers, data scientists, embedded systems developers, cybersecurity analysts, product managers, DevOps engineers, cloud architects, and IT support specialists are in high demand across healthcare, manufacturing, fintech, and SaaS startups.
How do remote and on‑site work trends look in Cleveland?
Most Cleveland employers offer hybrid models, with core office days for collaboration. Remote‑first companies such as GoDaddy and Progress Software provide flexible schedules, while manufacturing‑focused firms like Rockwell Automation prefer on‑site presence for hands‑on hardware work.
Who are the major tech employers in the area?
KeyCorp, Cleveland Clinic, Rockwell Automation, Progress Software, GoDaddy, Itron, KeyBank Digital, and Health Catalyst are top employers offering roles from R&D to operations.
What are the salary expectations for tech roles in Cleveland?
Software engineers average $90k–$120k, data scientists $95k–$130k, embedded engineers $85k–$110k, and cybersecurity analysts $80k–$105k, with senior roles reaching $140k+ depending on experience and specializations.
What advice should I follow when relocating to Cleveland for tech work?
Research neighborhoods with tech hubs—Ohio City, Tremont, and Downtown for proximity to offices. Use local co‑working spaces like The Hub at the Cleveland Institute of Art. Compare housing costs: $1,200–$1,500/month for apartments, and consider employer relocation packages that cover moving and housing stipends.

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