Tech Jobs in Greenville, SC
Greenville, the heart of Upstate South Carolina, offers a blend of Southern charm and a rapidly expanding tech scene. The city’s strategic location—just 120 miles from Atlanta and 200 miles from Charlotte—provides easy access to major markets while maintaining a low cost of living. Recent surveys show a 12% increase in tech talent density, driven by community events like the annual Greenville Tech Summit and a supportive ecosystem of co‑working spaces such as the Greenville Technology Center.
Tech employers in Greenville range from multinational giants to nimble startups. Epic Systems anchors the local healthcare IT landscape with roles in software engineering, data science, and cybersecurity. Medtronic and GE Healthcare offer opportunities in medical device software and embedded systems. Honeywell Aerospace and Dynatrace focus on cloud‑native monitoring and aerospace software. Emerging startups like Lattice (HR SaaS), Syntiant (AI chip design), and local incubator-backed firms provide roles in mobile development, UX, and product management.
The median home price in Greenville sits at roughly $210,000, below the national average, and the cost‑of‑living index is 73 compared to 100 nationwide. This affordability amplifies the value of transparent salary data—job seekers can accurately assess whether an offer aligns with local expenses, negotiate confidently, and plan long‑term financial goals.
Physical Medicine and Rehabilitation Opportunity
Company: Prisma Health
Location: Greenville, South Carolina
Posted Jun 30, 2025
Gastroenterology Hospitalist
Company: Prisma Health
Location: Greenville, South Carolina
Posted May 17, 2025
HOSPICE CLINICAL MANAGER - RN
Company: Liberty Health
Location: Greenville, North Carolina
Posted May 26, 2025
Emergency Psychiatry Opportunity
Company: Prisma Health
Location: Greenville, South Carolina
Posted Jul 13, 2025
Neurologist Opportunity in Upstate South Carolina
Company: CompHealth
Location: Greenville, South Carolina
Posted May 26, 2025
Pediatric and Adolescent Gynecologist
Company: Prisma Health
Location: Greenville, South Carolina
Posted May 19, 2025
OB-GYN Physician Needed in Beautiful Greenville, South Carolina
Company: CompHealth
Location: Greenville, South Carolina
Posted May 17, 2025
Gastroenterology Hospitalist
Company: Prisma Health
Location: Greenville, South Carolina
Posted Jun 03, 2025
Infectious Disease Physician
Company: Self Regional Healthcare - Physician
Location: Greenville, South Carolina
Posted Jun 01, 2025
PA Neurosurgery Opportunity in Greenville, NC
Company: ECU Health
Location: Greenville, North Carolina
Posted May 19, 2025
Physician - Gastroenterology
Company: Prisma Health
Location: Greenville, South Carolina
Posted May 19, 2025
Adolescent Medicine Specialist
Company: Prisma Health
Location: Greenville, South Carolina
Posted Jul 13, 2025