Tech Jobs in Greenville, SC

22,993 open positions · Updated daily

Greenville, the heart of Upstate South Carolina, offers a blend of Southern charm and a rapidly expanding tech scene. The city’s strategic location—just 120 miles from Atlanta and 200 miles from Charlotte—provides easy access to major markets while maintaining a low cost of living. Recent surveys show a 12% increase in tech talent density, driven by community events like the annual Greenville Tech Summit and a supportive ecosystem of co‑working spaces such as the Greenville Technology Center.

Tech employers in Greenville range from multinational giants to nimble startups. Epic Systems anchors the local healthcare IT landscape with roles in software engineering, data science, and cybersecurity. Medtronic and GE Healthcare offer opportunities in medical device software and embedded systems. Honeywell Aerospace and Dynatrace focus on cloud‑native monitoring and aerospace software. Emerging startups like Lattice (HR SaaS), Syntiant (AI chip design), and local incubator-backed firms provide roles in mobile development, UX, and product management.

The median home price in Greenville sits at roughly $210,000, below the national average, and the cost‑of‑living index is 73 compared to 100 nationwide. This affordability amplifies the value of transparent salary data—job seekers can accurately assess whether an offer aligns with local expenses, negotiate confidently, and plan long‑term financial goals.

Senior AWS Cloud Systems Engineer.

Company: Precise Software

Location: Charleston, SC

Posted Jan 24, 2023

None Found

Sr. Manager, MS&T

Company: Emergent BioSolutions

Location: Charleston, SC

Posted Jan 30, 2023

The job description is for a Technical Transfer Manager at Emergent BioSolutions, a company that aims to protect and enhance 1 billion lives by 2030. The role involves leading technical transfer of product/process manufacturing from one site to another, and working closely with internal and external partners. The job requires strong technical background, good communication skills, and ability to work independently.

Director, EFV

Company: Emergent BioSolutions

Location: Charleston, SC

Posted Jan 30, 2023

The job summary describes a leadership role at Emergent BioSolutions, where the individual will manage the Engineering, Facilities, and Validation (EFV) team and ensure site objectives are achieved. The role involves providing effective and collaborative cross-functional leadership, driving development of the EFV team and personal development of team members, and implementing EFV best practices and harmonization initiatives.

Art Director

Company: Chernoff Newman

Location: Charleston, SC

Posted Jan 30, 2023

The company is looking for an art director who is passionate about solving problems through creative communications. They value diversity of thought, people, and skillsets, and are committed to a workforce that is inclusive of their community and culture.

Accounting Account Manager

Company: Angela Adams Consulting Services

Location: Charleston, SC

Posted Jan 15, 2023

Angel Adams Consulting is a premier resource for agencies seeking advice, custom solutions, and remote services related to front and back-office insurance agency operations. They offer extensive job training, a flexible work schedule, and a supportive work environment. The role involves handling accounting needs, overseeing functions, communicating with clients and processors, and more.

Sr Engineer, MS&T

Company: Emergent BioSolutions

Location: Charleston, SC

Posted Jan 30, 2023

The job description is for a technical transfer process team leader at Emergent BioSolutions. The candidate will lead process validation activities, manufacturing process transfer, and technical transfer projects. The job requires strong leadership skills, experience with drug product manufacturing processes, and knowledge of sterile processing principles.

Reals Account Executive

Company: LendingTree

Location: Charleston, SC

Posted Jan 20, 2023

LendingTree is a company that connects customers with multiple lenders to find the best deals on loans, credit cards, and insurance. The company is looking for a Renewals Agent to manage a portfolio of existing customers and help them with their borrowing needs.

Senior Backend Software Engineer

Company: GoodUnited

Location: Charleston, SC

Posted Jan 17, 2023

GoodUnited employs Senior Backend Software Engineers to develop customizable conversational messaging systems across multiple platforms. These engineers create innovative solutions, provide technical input into product design, and translate user requirements into architecture and technical designs. They work closely with product managers and designers, and are expected to have a Bachelor's degree in computer science or a related field, along with 7-10 years of software engineering experience. Proficiency in NodeJS, Typescript, and API design/implementation is required. Experience with Docker, cloud platforms (preferably AWS), and the full software development lifecycle in an agile environment is also desired.

Customer Operations Associate

Company: Johnson Controls

Location: Charleston, SC

Posted Jan 28, 2023

None Found

Sr. Manager, MS&T

Company: Emergent BioSolutions

Location: Charleston, SC

Posted Jan 26, 2023

None Found

Accountant - Federal Consulting Services

Company: Chevo Consulting, LLC

Location: Charleston, SC

Posted Jan 14, 2023

Chevo is seeking an Accountant to work internally as part of the Chevo corporate staff. The job involves assisting the Controller with day-to-day accounting activities, including running payroll, processing expense reports, and performing accounts payable and receivable tasks. The company offers a comprehensive benefits package and is an Equal Opportunity Employer.

News Editor

Company: Sinclair Broadcast Group

Location: Charleston, SC

Posted Jan 24, 2023

None Found

Frequently Asked Questions

What types of tech jobs are available in Greenville, SC?
Greenville hosts a broad spectrum of tech roles: software engineers, data scientists, cybersecurity analysts, devOps engineers, product managers, UX/UI designers, QA testers, network engineers, and AI specialists. Epic Systems, Medtronic, and GE Healthcare frequently list positions in medical device software, while Dynatrace and Honeywell offer cloud and aerospace roles. Startups like Lattice and Syntiant add opportunities in SaaS development and AI hardware design.
Is remote work common for tech positions in Greenville, or is on‑site required?
Hybrid models dominate in Greenville. Companies such as Dynatrace and Lattice offer fully remote or flexible schedules, recognizing the talent pool across the state. Epic Systems and Medtronic typically require on‑site presence for collaboration on complex projects, though they provide hybrid options for certain data‑centric roles. Prospective hires should verify each employer’s policy during the interview process.
Which major employers dominate the Greenville tech market?
Key employers include Epic Systems (healthcare IT), Medtronic (medical devices), GE Healthcare (imaging software), Honeywell Aerospace (aerospace solutions), Dynatrace (cloud monitoring), Lattice (HR SaaS), and Syntiant (AI chip design). The city also hosts a growing number of fintech and cybersecurity startups supported by local incubators like the Greenville Technology Center.
What salary ranges can tech professionals expect in Greenville, SC?
Median salaries for core tech roles in Greenville hover around $100,000 for software engineers and $110,000 for data scientists. Cybersecurity analysts earn $95,000–$115,000, while devOps engineers command $90,000–$110,000. Senior roles or niche specialties can exceed $140,000. Salary transparency on Job Transparency allows candidates to benchmark offers against these local averages.
What should I consider when relocating to Greenville for tech work?
Prioritize neighborhoods with strong tech communities—Downtown Greenville, Galleria, and the West End offer proximity to offices, cafés, and networking venues. Research local school districts if you have children; the Greenville County School District is highly rated. Use the South Carolina Department of Labor’s cost‑of‑living calculator to compare housing and transportation costs. Engage with the Greenville Chamber of Commerce and attend local meetups to build connections before the move.

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