Tech Jobs in Peninsula

11,185 open positions · Updated daily

Peninsula sits between San Francisco and Silicon Valley, offering a unique blend of urban convenience and tech innovation. The region hosts over 300 high‑growth startups, from fintech leaders like Braintree in San Mateo to AI pioneers such as Petal. With climate‑friendly coastal breezes and easy access to major transit hubs, Peninsula draws talent who want both career momentum and a high quality of life.

Tech roles span software engineering, data science, cybersecurity, and product management across diverse sectors. Fintech firms like Braintree and Stripe (nearby Redwood City) dominate, while biotech powerhouses such as Gilead Sciences in South San Francisco and Seagen in Sunnyvale drive research and development. SaaS companies—Salesforce in San Mateo and Evergreen Software—and e‑commerce platforms like Petal keep the ecosystem thriving.

Living costs in Peninsula are some of the highest in the country; the median rent for a two‑bedroom apartment in San Mateo tops $3,200/month, and the median home price exceeds $1.5 million. Because of this, salary transparency helps candidates negotiate roles that match their financial expectations. With a median tech salary around $155,000, knowing the exact pay band can save years of uncertainty and ensure you get a package that reflects your experience and the local market.

Senior Principal Scientist/Associate Director, Bioinformatics

Company: Lyterian Therapeutics

Location: Peninsula

Posted Nov 26, 2024

Lyterian Therapeutics is seeking a Senior Principal Scientist/Associate Director Bioinformatics to develop and use computational approaches to characterize and analyze data generated from cutting-edge high-throughput screening approaches. The candidate will work closely with biologists, biophysicists, chemists, and structural biologists to uncover fundamental biology and advance drug discovery.

Principal Software Engineer - Network Transport

Company: Roblox

Location: Peninsula

Posted Nov 26, 2024

Roblox is building a platform to empower developers and creators to bring their imagination to life. The company is looking for talented individuals to help shape the future of human interaction and create safer, more civil shared experiences.

Pre-Sales Engineer

Company: Pathway (pathway.com)

Location: Peninsula

Posted Nov 26, 2024

Pathway is a VC-funded company offering a ultraperformant Data Processing Framework for enterprise use cases. They are backed by Business Angels and have operations across Europe and the US. The role involves being a trusted advisor and technical expert to customers, helping them make informed decisions about Pathway's solutions.

Staff Hardware Reliability Engineer

Company: Aurora

Location: Peninsula

Posted Nov 26, 2024

Aurora is a company that is working on self-driving technology to make transportation safer, more accessible, and efficient. They are hiring talented people with diverse backgrounds to help build a transportation ecosystem. The company has a strong focus on safety, diversity, and inclusion, and offers competitive benefits and opportunities for growth.

Senior Buyer

Company: Guardant Health

Location: Peninsula

Posted Nov 25, 2024

The job description is for a Senior Buyer at Guardant Health, a leading precision oncology company. The role involves managing inventory levels, overseeing logistics, and collaborating with internal teams to ensure timely material availability and cost management.

(Senior) Director, CMC

Company: Insitro

Location: Peninsula

Posted Nov 26, 2024

insitro is a drug discovery and development company using machine learning and data at scale to decode biology for transformative medicines. They are advancing a wholly owned and partnered pipeline of insights and therapeutics in neuroscience, oncology, and metabolism. The company has raised over $700 million from top tech biotech and crossover investors and from collaborations with pharmaceutical partners.

Data Science, Product

Company: Glean

Location: Peninsula

Posted Nov 26, 2024

Glean is a company that aims to make knowledge work faster and more humane by building a system of intelligence for every company in the world. They are building a world-class data organization and are looking for a data scientist to join their team.

Staff Software Engineer

Company: Twist Bioscience

Location: Peninsula

Posted Nov 26, 2024

Twist Bioscience is seeking a Staff Software Engineer to join their dynamic team. The ideal candidate will have experience in designing, developing, and maintaining scalable software systems, as well as working with complex architectural ecosystems. The role offers a competitive base cash compensation, bonus, equity, and a generous benefits package.

Senior Microscopy Hardware Engineer, Automation

Company: Insitro

Location: Peninsula

Posted Nov 26, 2024

The text describes a job opening for a Senior Microscopy Hardware Engineer at insitros, a biotech startup focused on drug discovery and development using machine learning and data at scale. The role involves standardizing the imaging fleet, maintaining and managing microscopy equipment, and collaborating with various teams to develop predictive maintenance methods and identify common failures. The company offers competitive compensation, benefits, and a supportive work environment.

Field Service Engineer Manager

Company: Gator Bio

Location: Peninsula

Posted Nov 26, 2024

Gator Bio is a preIPO biotech company that develops innovative technologies for healthcare industries. The company is looking for a Field Service Engineer Manager to lead a team and ensure optimal performance and support for their instrumentation solutions.

Backend Software Engineer

Company: TabaPay

Location: Peninsula

Posted Nov 26, 2024

TabaPay is a leading fintech company that provides instant digital payments solutions. They are looking for a backend software engineer to design and build new payment solutions.

People Ops Coordinator (Contract)

Company: Adverum Biotechnologies

Location: Peninsula

Posted Nov 26, 2024

Adverum is seeking a People Operations Coordinator for a contract-to-hire position. The role involves new hire onboarding, HR tracker maintenance, employee service, and support for HR programs. The ideal candidate is a Bachelor's degree holder with 25+ years of experience as an HR Coordinator or Admin, with strong communication, problem-solving, and organizational skills.

Frequently Asked Questions

What types of tech jobs are available in Peninsula?
The Peninsula hosts a wide array of tech roles, including software engineering, front‑end and back‑end development, data science, machine learning, cybersecurity, product management, user experience design, and DevOps. Positions range from junior to senior levels, with many companies offering both full‑time and contract opportunities.
How do remote and on‑site trends look in Peninsula tech jobs?
While Peninsula companies increasingly adopt hybrid models, many still prioritize on‑site presence due to collaborative culture and proximity to headquarters. Remote roles are common in larger firms like Salesforce, but most startups prefer on‑site or hybrid arrangements to foster teamwork and rapid iteration.
Which are the major employers for tech talent in Peninsula?
Key employers include <strong>Braintree</strong> (San Mateo), <strong>Petal</strong> (San Mateo), <strong>Gilead Sciences</strong> (South San Francisco), <strong>Seagen</strong> (Sunnyvale), <strong>Salesforce</strong> (San Mateo), and <strong>Stripe</strong> (Redwood City). Additionally, biotech and AI firms such as <strong>Seagen</strong> and <strong>Petal</strong> drive significant hiring.
What are the salary expectations for tech roles in Peninsula?
Median base salaries for tech positions in Peninsula hover around $155,000, with senior engineers earning $180,000–$220,000 and product managers ranging from $140,000 to $190,000. Compensation packages often include bonuses, equity, and comprehensive benefits, reflecting the high cost of living and market demand.
What should I know about relocating to Peninsula for tech work?
When moving to Peninsula, budget for premium housing—average rent for a two‑bedroom apartment exceeds $3,200/month. Explore neighborhoods like San Mateo, Foster City, and South San Francisco for a mix of affordability and commute options.

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