Tech Jobs in SAN DIEGO, California

1,135,792 open positions · Updated daily

San Diego's tech scene is booming. The city blends a mild climate, top universities, and a diversified economy that fuels rapid growth in biotech, defense, gaming, and clean‑tech startups. With 3,230 openings, recruiters prioritize local talent for roles ranging from bioinformatics to cybersecurity, making it a prime destination for tech professionals who want both innovation and a high quality of life.

San Diego hosts world‑renowned biotech labs like Genentech and Illumina, defense giants such as Lockheed Martin and Raytheon, and gaming leaders like Zynga and Nintendo of America. The city’s research hubs in La Jolla and Sorrento Valley attract software engineers, data scientists, and AI specialists, while companies in renewable energy—Tesla Energy and SolarCity—drive sustainable tech roles. Startup culture thrives in Mission Valley, offering roles in fintech, healthtech, and AR/VR.

Housing prices in San Diego top the national average, with median home values near $950,000 and a two‑bedroom apartment costing roughly $2,500/month. That makes salary transparency essential; knowing exact compensation helps candidates plan for the high cost of living, negotiate benefits, and choose neighborhoods that fit their lifestyle.

Class A CDL Truck Driver - Home Daily - $1255 Weekly Min - MIN EXP REQ

Company: HandledNow+

Location: San Antonio, TX

Posted Aug 22, 2025

Must have a valid Class A CDL License. Must have at least 9 months of tractor trailer experience in the last 3 years (Or 2 years in last 5, or 5 year in last 10…

Program Development Manager, Professional Education

Company: American Heart Association

Location: San Antonio, TX

Posted Aug 22, 2025

Manage program related vendors including those who handle case-based outcomes surveys, those who develop and host program websites or activities, and those who…

Mainframe Security Analyst, Officer

Company: Citi

Location: San Antonio, TX

Posted Aug 22, 2025

This role will play a crucial part in ensuring the security and compliance of our enterprise mainframe systems, supporting automation efforts, and driving…

Classified Substitute

Company: Union School District

Location: San Jose, CA

Posted Aug 22, 2025

The District is situated between the beautiful Los Gatos foothills and the city of San Jose. The District occupies the southwest corner of Santa Clara County…

Concrete Laborer- Sign installer

Company: OnSight Industries LLC

Location: San Antonio, TX

Posted Aug 22, 2025

Valid driver license and clean motor vehicle record. Some hand tools (impact drill, tape measure, levels, etc.). Reading and interpreting plans or drawings.

Staff Nurse

Company: University Health

Location: San Antonio, TX

Posted Aug 22, 2025

Current RN license from the Texas Board of Nursing. Comprehensive benefits package including pet insurance. RN Student Loan Repayment Program.

CDL A OTR Truck Driver - $1250 orientation pay

Company: Central Oregon Truck Company

Location: California

Posted Aug 22, 2025

Top drivers *earn up to $127,000 per year\**. *No Flatbed experience required* for experienced OTR drivers – Get trained for Flatbed during orientation.

Manager, Data Science - GenAI Digital Assistant

Company: Capital One

Location: San Jose, CA

Posted Aug 22, 2025

A PhD in a quantitative field (Statistics, Economics, Operations Research, Analytics, Mathematics, Computer Science, or a related quantitative field) plus 1…

CDL A OTR Truck Driver - $1250 orientation pay

Company: Central Oregon Truck Company

Location: San Diego, CA

Posted Aug 22, 2025

Central Oregon Trucking Company is hiring experienced CDL A truck drivers seeking industry-leading pay and benefits and ready to haul flatbed freight with the…

Trainee

Company: L&S Mechanical

Location: San Antonio, TX

Posted Aug 22, 2025

Prior experience as a plumbing, electrical or HVAC helper in residential, new construction preferred, but not required. Medical, dental and vision insurance.

Principal Data Scientist, AI Foundations

Company: Capital One

Location: San Jose, CA

Posted Aug 22, 2025

A Bachelor's Degree in a quantitative field (Statistics, Economics, Operations Research, Analytics, Mathematics, Computer Science, or a related quantitative…

Accountant I/II

Company: Santa Clara County Office of Education

Location: San Jose, CA

Posted Aug 22, 2025

The Accountant I/II performs professional accounting, budget analysis and reviews, and provides comprehensive fiscal knowledge, accounting/fiscal support, and…

Frequently Asked Questions

What types of tech jobs are available in San Diego?
San Diego offers roles for software engineers, data scientists, AI/ML engineers, bioinformatics analysts, cybersecurity specialists, cloud architects, product managers, UI/UX designers, and embedded systems developers. Positions span biotech R&D, defense systems, gaming development, renewable energy control systems, and fintech platforms.
Are most tech jobs remote or on-site?
While many companies offer hybrid or fully remote options, about 60% of tech roles in San Diego still prefer on-site presence, especially in biotech labs, defense contractors, and gaming studios that rely on collaboration and secure facilities. Remote-friendly roles often focus on software development, data analysis, and cloud services.
Who are the major employers in San Diego's tech sector?
Key employers include Genentech, Illumina, Biogen, Lockheed Martin, Raytheon Technologies, Northrop Grumman, Zynga, Nintendo of America, Cisco Systems, Google, Tesla Energy, and numerous biotech startups in La Jolla and Sorrento Valley.
What salary can I expect for tech roles in San Diego?
Salaries vary by role and experience. Entry‑level software engineers earn $90‑110k, mid‑level $120‑150k, senior roles $160‑210k. Data scientists start at $95‑125k, AI/ML engineers $110‑150k, cybersecurity specialists $100‑140k. Biotech roles often command higher pay, with senior scientists earning $180‑220k. Benefits and bonuses add 10‑20% to base pay.
What should I know about relocating to San Diego for tech work?
Research neighborhoods—La Jolla, Mission Valley, and Pacific Beach offer proximity to tech hubs; consider commute, cost, and lifestyle. Secure housing early; negotiate relocation assistance and housing allowances. Network through local meetups like SDTech and the San Diego Startup Week. Familiarize yourself with California tax and cost of living before accepting offers.

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