Tech Jobs in SAN DIEGO, California

1,135,969 open positions · Updated daily

San Diego's tech scene is booming. The city blends a mild climate, top universities, and a diversified economy that fuels rapid growth in biotech, defense, gaming, and clean‑tech startups. With 3,230 openings, recruiters prioritize local talent for roles ranging from bioinformatics to cybersecurity, making it a prime destination for tech professionals who want both innovation and a high quality of life.

San Diego hosts world‑renowned biotech labs like Genentech and Illumina, defense giants such as Lockheed Martin and Raytheon, and gaming leaders like Zynga and Nintendo of America. The city’s research hubs in La Jolla and Sorrento Valley attract software engineers, data scientists, and AI specialists, while companies in renewable energy—Tesla Energy and SolarCity—drive sustainable tech roles. Startup culture thrives in Mission Valley, offering roles in fintech, healthtech, and AR/VR.

Housing prices in San Diego top the national average, with median home values near $950,000 and a two‑bedroom apartment costing roughly $2,500/month. That makes salary transparency essential; knowing exact compensation helps candidates plan for the high cost of living, negotiate benefits, and choose neighborhoods that fit their lifestyle.

mentorship professional growth supportive leadership

Neuroendovascular Neurosurgeon in Los Angeles

Company: No Employer

Location: Beverly Hills, California

Posted Aug 17, 2025

View Details Apply on healthecareers.com

hospital part-time

Temporary Seasonal Staff RN Hospital - Med/Surg/Tele - Part Time, Nights

Company: Kaiser Permanente

Location: Downey, California

Posted Aug 17, 2025

View Details Apply on healthecareers.com

sign-on bonus hospital full-time

Exciting OB/GYN Hospitalist Leadership Opportunity in La Mesa, CA

Company: Ob Hospitalist Group

Location: La Mesa, California

Posted Aug 17, 2025

View Details Apply on healthecareers.com

travel 401(k) life insurance

Occupational Therapist - Skilled - (OT)

Company: AMN Healthcare, Inc. Medical

Location: RIVERSIDE, California

Posted Aug 17, 2025

View Details Apply on healthecareers.com

Registered Nurse-Ambulatory Surgery Center Stone Oak

Company: Christus Health

Location: San Antonio, TX

Posted Aug 17, 2025

Continues to develop the ability to cope with and manage contingencies of clinical nursing. RN License in state of employment or compact.

View Details Apply on SimplyHired

loan repayment program sign-on bonus contract

Speech Therapist II, Pediatrics, 40 Hours

Company: Kaiser Permanente

Location: Vacaville, California

Posted Aug 17, 2025

View Details Apply on healthecareers.com

full-time

LVN II-Panorama City MOB #6-Evening Urgent Care-On Call

Company: Kaiser Permanente

Location: Los Angeles, California

Posted Aug 17, 2025

View Details Apply on healthecareers.com

RN, Registered Nurse - Pre Operative

Company: Christus Health

Location: San Antonio, TX

Posted Aug 17, 2025

Continues to develop the ability to cope with and manage contingencies of clinical nursing. RN License in state of employment or compact.

View Details Apply on SimplyHired

403(b) 457(b) dental insurance

EP Cardiology in Monterey Bay Area, CA | 750k Base Salary

Company: Jackson Physician Search

Location: California

Posted Aug 17, 2025

View Details Apply on healthecareers.com

research

Research Associate I- On Call

Company: Kaiser Permanente

Location: Pleasanton, California

Posted Aug 17, 2025

View Details Apply on healthecareers.com

full-time

Sterile Processing Technician II Certified - On Call

Company: Kaiser Permanente

Location: Richmond, California

Posted Aug 17, 2025

View Details Apply on healthecareers.com

RN, Registered Nurse - Acute MedSurgical A

Company: Christus Health

Location: San Antonio, TX

Posted Aug 17, 2025

Continues to develop the ability to cope with and manage contingencies of clinical nursing. RN License in state of employment or compact.

View Details Apply on SimplyHired

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Frequently Asked Questions

What types of tech jobs are available in San Diego?

San Diego offers roles for software engineers, data scientists, AI/ML engineers, bioinformatics analysts, cybersecurity specialists, cloud architects, product managers, UI/UX designers, and embedded systems developers. Positions span biotech R&D, defense systems, gaming development, renewable energy control systems, and fintech platforms.

Are most tech jobs remote or on-site?

While many companies offer hybrid or fully remote options, about 60% of tech roles in San Diego still prefer on-site presence, especially in biotech labs, defense contractors, and gaming studios that rely on collaboration and secure facilities. Remote-friendly roles often focus on software development, data analysis, and cloud services.

Who are the major employers in San Diego's tech sector?

Key employers include Genentech, Illumina, Biogen, Lockheed Martin, Raytheon Technologies, Northrop Grumman, Zynga, Nintendo of America, Cisco Systems, Google, Tesla Energy, and numerous biotech startups in La Jolla and Sorrento Valley.

What salary can I expect for tech roles in San Diego?

Salaries vary by role and experience. Entry‑level software engineers earn $90‑110k, mid‑level $120‑150k, senior roles $160‑210k. Data scientists start at $95‑125k, AI/ML engineers $110‑150k, cybersecurity specialists $100‑140k. Biotech roles often command higher pay, with senior scientists earning $180‑220k. Benefits and bonuses add 10‑20% to base pay.

What should I know about relocating to San Diego for tech work?

Research neighborhoods—La Jolla, Mission Valley, and Pacific Beach offer proximity to tech hubs; consider commute, cost, and lifestyle. Secure housing early; negotiate relocation assistance and housing allowances. Network through local meetups like SDTech and the San Diego Startup Week. Familiarize yourself with California tax and cost of living before accepting offers.

Tech Jobs in SAN DIEGO, California

Frequently Asked Questions

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