Tech Jobs in SAN DIEGO, California

1,136,106 open positions · Updated daily

San Diego's tech scene is booming. The city blends a mild climate, top universities, and a diversified economy that fuels rapid growth in biotech, defense, gaming, and clean‑tech startups. With 3,230 openings, recruiters prioritize local talent for roles ranging from bioinformatics to cybersecurity, making it a prime destination for tech professionals who want both innovation and a high quality of life.

San Diego hosts world‑renowned biotech labs like Genentech and Illumina, defense giants such as Lockheed Martin and Raytheon, and gaming leaders like Zynga and Nintendo of America. The city’s research hubs in La Jolla and Sorrento Valley attract software engineers, data scientists, and AI specialists, while companies in renewable energy—Tesla Energy and SolarCity—drive sustainable tech roles. Startup culture thrives in Mission Valley, offering roles in fintech, healthtech, and AR/VR.

Housing prices in San Diego top the national average, with median home values near $950,000 and a two‑bedroom apartment costing roughly $2,500/month. That makes salary transparency essential; knowing exact compensation helps candidates plan for the high cost of living, negotiate benefits, and choose neighborhoods that fit their lifestyle.

Registered Nurse FT

Company: GCSA Ambulatory Surgery Center - Medical Center (12367)

Location: San Antonio, TX

Posted Aug 14, 2025

Must be a Registered Nurse with an unrestricted license in the state. Perform all nursing duties in accordance with the state Nursing Practice Act, while…

Custodian

Company: Fleet Science Center

Location: San Diego, CA

Posted Aug 14, 2025

Vacuum lobby, science center, theater, lecture hall, and staff offices. General Statement: The Reuben H. Fleet Science Centers Custodian supports the Fleet…

Sr. Cloud Security Architect-San Antonio, Dallas, Austin, TX

Company: H‑E‑B

Location: San Antonio, TX

Posted Aug 14, 2025

Works with internal Information Systems teams to design security controls and improve cloud security infrastructure to support business/engineering needs.

Senior Software Engineer-Data Solutions (San Antonio, Austin, and Dallas)

Company: HEB

Location: San Antonio, TX

Posted Aug 14, 2025

Advanced knowledge in system and data architecture, data modeling, and design and capable of architecting and designing at the application or service level…

Registered Nurse (RN) - Infection Control - 5x8 Days

Company: Centra Healthcare Solutions

Location: San Diego, CA

Posted Aug 14, 2025

Current Registered Nurse (RN) license within the state of practice. Centra Healthcare Solutions is seeking an experienced Registered Nurse (RN) that is licensed…

Sales Consultant - Jaguar Land Rover of San Antonio

Company: Cavender Auto Group

Location: San Antonio, TX

Posted Aug 14, 2025

Valid driver's license and clean driving record. Work directly with our employees and customers to develop relationships and help to enhance the sales process.

Senior GRC Analyst-Risk Management-San Antonio, TX

Company: HEB

Location: San Antonio, TX

Posted Aug 14, 2025

Our Digital Technology Partners collaborate to design, construct, implement, and support technology solutions, using the best available technologies to deliver…

Financial Analyst II - Project Management

Company: HEB

Location: San Antonio, TX

Posted Aug 14, 2025

Corporate Planning & Analysis develops / maintains budgets and financial systems while providing current, reliable financial data, analysis, and technical info.

Block Advisor Tax Advisor

Company: H&R Block

Location: San Antonio, TX

Posted Aug 14, 2025

Bachelor’s degree in accounting or related field. CPA or Enrolled Agent certification. All certification levels can provide tax notice services.

Registered Nurse, Home Health

Company: AccentCare, Inc.

Location: San Diego, CA

Posted Aug 14, 2025

Must be a licensed driver with an automobile that is insured in accordance with state and/or organization requirements and is in good working order.

Frequently Asked Questions

What types of tech jobs are available in San Diego?
San Diego offers roles for software engineers, data scientists, AI/ML engineers, bioinformatics analysts, cybersecurity specialists, cloud architects, product managers, UI/UX designers, and embedded systems developers. Positions span biotech R&D, defense systems, gaming development, renewable energy control systems, and fintech platforms.
Are most tech jobs remote or on-site?
While many companies offer hybrid or fully remote options, about 60% of tech roles in San Diego still prefer on-site presence, especially in biotech labs, defense contractors, and gaming studios that rely on collaboration and secure facilities. Remote-friendly roles often focus on software development, data analysis, and cloud services.
Who are the major employers in San Diego's tech sector?
Key employers include Genentech, Illumina, Biogen, Lockheed Martin, Raytheon Technologies, Northrop Grumman, Zynga, Nintendo of America, Cisco Systems, Google, Tesla Energy, and numerous biotech startups in La Jolla and Sorrento Valley.
What salary can I expect for tech roles in San Diego?
Salaries vary by role and experience. Entry‑level software engineers earn $90‑110k, mid‑level $120‑150k, senior roles $160‑210k. Data scientists start at $95‑125k, AI/ML engineers $110‑150k, cybersecurity specialists $100‑140k. Biotech roles often command higher pay, with senior scientists earning $180‑220k. Benefits and bonuses add 10‑20% to base pay.
What should I know about relocating to San Diego for tech work?
Research neighborhoods—La Jolla, Mission Valley, and Pacific Beach offer proximity to tech hubs; consider commute, cost, and lifestyle. Secure housing early; negotiate relocation assistance and housing allowances. Network through local meetups like SDTech and the San Diego Startup Week. Familiarize yourself with California tax and cost of living before accepting offers.

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