Tech Jobs in SAN DIEGO, California

1,136,496 open positions · Updated daily

San Diego's tech scene is booming. The city blends a mild climate, top universities, and a diversified economy that fuels rapid growth in biotech, defense, gaming, and clean‑tech startups. With 3,230 openings, recruiters prioritize local talent for roles ranging from bioinformatics to cybersecurity, making it a prime destination for tech professionals who want both innovation and a high quality of life.

San Diego hosts world‑renowned biotech labs like Genentech and Illumina, defense giants such as Lockheed Martin and Raytheon, and gaming leaders like Zynga and Nintendo of America. The city’s research hubs in La Jolla and Sorrento Valley attract software engineers, data scientists, and AI specialists, while companies in renewable energy—Tesla Energy and SolarCity—drive sustainable tech roles. Startup culture thrives in Mission Valley, offering roles in fintech, healthtech, and AR/VR.

Housing prices in San Diego top the national average, with median home values near $950,000 and a two‑bedroom apartment costing roughly $2,500/month. That makes salary transparency essential; knowing exact compensation helps candidates plan for the high cost of living, negotiate benefits, and choose neighborhoods that fit their lifestyle.

Staff Software Engineer, AI/Machine Learning

Company: PSEMI CORPORATION

Location: San Diego, CA

Posted Aug 09, 2025

As a Staff Software Engineer specializing in AI/ML, you will be entrusted with end-to-end ownership of designing, developing, and deploying state-of-the-art AI/…

Data Scientist, Financial Crimes - USDS

Company: TikTok

Location: San Jose, CA

Posted Aug 09, 2025

Collaborate with internal stakeholders to design, develop, validate, and implement AML scenarios, and conduct threshold tuning to optimize performance.

Product Engineering Architect

Company: Deloitte

Location: San Antonio, TX

Posted Aug 09, 2025

Technical Leadership and Advocacy: Serve as the technical advocate for products, ensuring architectural integrity, feasibility, and alignment with business and…

IT Enterprise Architect / Hybrid / Full Time (534)

Company: Sharp Community Medical Group

Location: San Diego, CA

Posted Aug 09, 2025

10+ years in solution design, system integration, or technical architecture. We’re seeking an IT Enterprise Architect to serve as a strategic, hands-on…

Armed Waterborne Security Officers – Full-Time

Company: Six Maritime

Location: San Diego, CA

Posted Aug 09, 2025

Meet all state/local licensing requirements before employment. Ability to pass a background check in accordance with federal, state, and local laws.

RN, Registered Nurse - Postpartum

Company: Christus Health

Location: San Antonio, TX

Posted Aug 09, 2025

Current STABLE (Post-resuscitation/Pre-transport Stabilization Care of Sick Infants) certification required from one of the following courses: Participant, Lead…

Residential and Commercial Cleaner

Company: Sparkle Grove Cleaning

Location: San Diego, CA

Posted Aug 09, 2025

In this role, you will be responsible for maintaining cleanliness and hygiene in residential and commercial spaces.

(RN) Registered Nurse - MON Pain Clinic

Company: UC San Diego Health

Location: San Diego, CA

Posted Aug 09, 2025

This RN will also provide coverage for sick calls, vacation, and messaging coverage for the pain clinic team. Federal, state, or local public health directives…

Machining - Assembly Operator 2nd shift

Company: Chromalloy

Location: San Antonio, TX

Posted Aug 09, 2025

Any offer of employment will also be conditioned upon the successful completion of a background investigation and drug screen in accordance with company policy…

Information Security Analyst, Senior

Company: Booz Allen

Location: San Antonio, TX

Posted Aug 09, 2025

You’ll be the key to discovering and correlating timely threat intel and deciphering what represents a real risk, and you’ll play an active role in incident…

Regional Security Manager

Company: Deloitte

Location: San Antonio, TX

Posted Aug 09, 2025

Bachelor's degree from an accredited four-year college or university in Criminal Justice,Security Management or a related field.

Manager, GenAI Engineer

Company: Deloitte

Location: San Antonio, TX

Posted Aug 09, 2025

A bachelor's degree in computer science, software engineering, or a related discipline. The ideal candidate will be a dependable team player and mentor,…

Frequently Asked Questions

What types of tech jobs are available in San Diego?
San Diego offers roles for software engineers, data scientists, AI/ML engineers, bioinformatics analysts, cybersecurity specialists, cloud architects, product managers, UI/UX designers, and embedded systems developers. Positions span biotech R&D, defense systems, gaming development, renewable energy control systems, and fintech platforms.
Are most tech jobs remote or on-site?
While many companies offer hybrid or fully remote options, about 60% of tech roles in San Diego still prefer on-site presence, especially in biotech labs, defense contractors, and gaming studios that rely on collaboration and secure facilities. Remote-friendly roles often focus on software development, data analysis, and cloud services.
Who are the major employers in San Diego's tech sector?
Key employers include Genentech, Illumina, Biogen, Lockheed Martin, Raytheon Technologies, Northrop Grumman, Zynga, Nintendo of America, Cisco Systems, Google, Tesla Energy, and numerous biotech startups in La Jolla and Sorrento Valley.
What salary can I expect for tech roles in San Diego?
Salaries vary by role and experience. Entry‑level software engineers earn $90‑110k, mid‑level $120‑150k, senior roles $160‑210k. Data scientists start at $95‑125k, AI/ML engineers $110‑150k, cybersecurity specialists $100‑140k. Biotech roles often command higher pay, with senior scientists earning $180‑220k. Benefits and bonuses add 10‑20% to base pay.
What should I know about relocating to San Diego for tech work?
Research neighborhoods—La Jolla, Mission Valley, and Pacific Beach offer proximity to tech hubs; consider commute, cost, and lifestyle. Secure housing early; negotiate relocation assistance and housing allowances. Network through local meetups like SDTech and the San Diego Startup Week. Familiarize yourself with California tax and cost of living before accepting offers.

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