Tech Jobs in SAN DIEGO, California

1,135,792 open positions · Updated daily

San Diego's tech scene is booming. The city blends a mild climate, top universities, and a diversified economy that fuels rapid growth in biotech, defense, gaming, and clean‑tech startups. With 3,230 openings, recruiters prioritize local talent for roles ranging from bioinformatics to cybersecurity, making it a prime destination for tech professionals who want both innovation and a high quality of life.

San Diego hosts world‑renowned biotech labs like Genentech and Illumina, defense giants such as Lockheed Martin and Raytheon, and gaming leaders like Zynga and Nintendo of America. The city’s research hubs in La Jolla and Sorrento Valley attract software engineers, data scientists, and AI specialists, while companies in renewable energy—Tesla Energy and SolarCity—drive sustainable tech roles. Startup culture thrives in Mission Valley, offering roles in fintech, healthtech, and AR/VR.

Housing prices in San Diego top the national average, with median home values near $950,000 and a two‑bedroom apartment costing roughly $2,500/month. That makes salary transparency essential; knowing exact compensation helps candidates plan for the high cost of living, negotiate benefits, and choose neighborhoods that fit their lifestyle.

Public Health Data Scientist

Company: Methodist Healthcare Ministries

Location: San Antonio, TX

Posted Oct 16, 2025

Must be able to drive and have access to a vehicle; maintain valid driver’s license and auto liability insurance. Translate analyses to a variety of audiences.

Janitors/Outdoor Porters - Now Hiring in San Antonio, TX!

Company: Federal Building Services

Location: San Antonio, TX

Posted Oct 16, 2025

*must have a valid driver's license and pass MVR check*. *must be able to work outside in all kinds of weather*. Other cleaning tasks that may be assigned.

Machine Operator

Company: Cox Manufacturing

Location: San Antonio, TX

Posted Oct 16, 2025

Troubleshoot machine issues and adjust settings to ensure machines are running smoothly. Operate CNC or automated Lathe machines to produce high-precision and…

HVAC Service Tech

Company: L&S Mechanical

Location: San Antonio, TX

Posted Oct 16, 2025

Job SummaryAs a HVAC service technician at L&S, you will repair and calibrate systems and replace various components. Medical, dental and vision insurance.

Digital Marketing Specialist

Company: RED MCCOMBS HYUNDAI

Location: San Antonio, TX

Posted Oct 16, 2025

As a Digital Marketing Specialist, you will be at the forefront of our marketing efforts, driving engagement and growth through innovative digital strategies.

OTR Class A Dry Van Driver

Company: Clean Harbors

Location: San Diego, CA

Posted Oct 16, 2025

Compensation includes hourly wages (all on-duty non-driving time) and mileage pay. 12+ months of Class A driving experience. Drivers average $80-$110K per year.

Property Manager

Company: Confidential

Location: San Diego, CA

Posted Oct 16, 2025

*Compliance:* Adhere to all local, state, and federal regulations as well as company policies and procedures. *Leasing:* Market and lease homes and apartments.

On-Call (1 weekend per month) Registered Nurse (RN) $50 hr

Company: Abundant Staffing

Location: San Antonio, TX

Posted Oct 16, 2025

Direct and supervise nurses, nurse assistants and nurse aides. Counsel and educate patients and their families on treatment plans. *Copy of a Negative TB Test*.

Machine Operator

Company: Cox Precision Manufacturing

Location: San Antonio, TX

Posted Oct 16, 2025

Troubleshoot machine issues and adjust settings to ensure excellent production. Adjust and change tooling as required to maintain product quality.

Builder (Deck, patio covers, outdoor living)

Company: French's Custom Outdoor Concepts

Location: San Antonio, TX

Posted Oct 16, 2025

Applicant would be responsible for moving job materials, laying out design and construction. Travel to surrounding areas of San Antonio.

Custodian- Little Flower Catholic School

Company: Little Flower School

Location: San Antonio, TX

Posted Oct 16, 2025

Meets with and monitors work of outside contractors. Communicates maintenance and repair issues to the principal. FLSA Status: Non-Exempt (Hourly).

Skilled General Construction Laborer

Company: Platinum Paving

Location: San Antonio, TX

Posted Oct 16, 2025

Must have a valid driver’s license. Knowledge of basic power tools and hand tools. Must be able to travel out of state. Knowledge of heavy equipment operations.

Frequently Asked Questions

What types of tech jobs are available in San Diego?
San Diego offers roles for software engineers, data scientists, AI/ML engineers, bioinformatics analysts, cybersecurity specialists, cloud architects, product managers, UI/UX designers, and embedded systems developers. Positions span biotech R&D, defense systems, gaming development, renewable energy control systems, and fintech platforms.
Are most tech jobs remote or on-site?
While many companies offer hybrid or fully remote options, about 60% of tech roles in San Diego still prefer on-site presence, especially in biotech labs, defense contractors, and gaming studios that rely on collaboration and secure facilities. Remote-friendly roles often focus on software development, data analysis, and cloud services.
Who are the major employers in San Diego's tech sector?
Key employers include Genentech, Illumina, Biogen, Lockheed Martin, Raytheon Technologies, Northrop Grumman, Zynga, Nintendo of America, Cisco Systems, Google, Tesla Energy, and numerous biotech startups in La Jolla and Sorrento Valley.
What salary can I expect for tech roles in San Diego?
Salaries vary by role and experience. Entry‑level software engineers earn $90‑110k, mid‑level $120‑150k, senior roles $160‑210k. Data scientists start at $95‑125k, AI/ML engineers $110‑150k, cybersecurity specialists $100‑140k. Biotech roles often command higher pay, with senior scientists earning $180‑220k. Benefits and bonuses add 10‑20% to base pay.
What should I know about relocating to San Diego for tech work?
Research neighborhoods—La Jolla, Mission Valley, and Pacific Beach offer proximity to tech hubs; consider commute, cost, and lifestyle. Secure housing early; negotiate relocation assistance and housing allowances. Network through local meetups like SDTech and the San Diego Startup Week. Familiarize yourself with California tax and cost of living before accepting offers.

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